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research Poly(rC) Binding Protein 2 Acts as a Negative Regulator of IRES-Mediated Translation of Hr mRNA

3 citations , February 2018 in “Experimental and Molecular Medicine/Experimental and molecular medicine”

A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.

research Vitamin D Receptor-Mediated Control of Soggy, Wise, and Hairless Gene Expression in Keratinocytes

13 citations , November 2013 in “Journal of Endocrinology/Journal of endocrinology”

Vitamin D receptor helps control hair growth genes in skin cells.

research The Hairless Gene of the Mouse: Relationship of Phenotypic Effects with Expression Profile and Genotype

52 citations , October 1999 in “Developmental Dynamics”

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

research Development and Progression of Alopecia in the Vitamin D Receptor Null Mouse

81 citations , January 2006 in “Journal of cellular physiology”

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

research Unveiling the Roots of Monogenic Genodermatoses: Genotrichoses as a Paradigm

26 citations , December 2011 in “Journal of Investigative Dermatology”

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

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community Minoxidil is a 5ar inhibitor according to research

in Research/Science 30 upvotes 17 hours ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 2 years ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community The DEFINITIVE cure for hairloss

in Satire 270 upvotes 3 months ago

The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 22 upvotes 4 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

in Minoxidil 35 upvotes 11 months ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

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