September 2017 in “Journal of Investigative Dermatology”
This study found that after four weeks of daily use, the roughness of the hairsurface significantly decreased, as shown through quantitative image analysis using HIROX.
In this study, a polyphenol and biotin supplement improved skin roughness and significantly reduced hair shedding, but did not demonstrate clear superiority over placebo in overall skin outcomes.
10 citations
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January 2020 in “Royal Society Open Science”
This study developed a quantitative measure for scoring hairsurface damage from SEM images and found it accurately classified hair damage caused by explosive blasts, similar to an existing classification system.
19 citations
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July 2018 in “ACS biomaterials science & engineering”
This study showed that chemical and mechanical treatments significantly alter the nanoscale surface properties of hair, affecting its roughness, mechanical stiffness, adhesion, and surface potential.
April 2023 in “Journal of Investigative Dermatology”
In this study, the researchers found that a combination of honeys from four islands significantly repaired hair integrity, porosity, and surfaceroughness caused by UV-A and urban pollution, resulting in strengthened, soft, and shiny hair in Asian hair shafts.
Hair regrowth on wounded and bald skin may be possible by activating the sonic hedgehog gene, leading to hair regrowth in mice. The findings are promising but may not directly apply to humans.
Hair regrowth after shedding typically takes 4-6 months, with variations depending on individual hair growth cycles. Finasteride can cause shedding, but new hair will grow back at its natural rate.
Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.
Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.