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Did you mean Hair Shaft Defects?

Glossary Hair Shaft Defects

refer to structural abnormalities in hair strands

Hair Shaft Defects refer to abnormalities in the structure of the hair strand that can lead to issues like brittleness, breakage, and an overall unhealthy appearance. These defects can be caused by genetic conditions, environmental damage, or improper hair care practices, and they often require specific treatments or changes in hair care routines to manage effectively.

Related Terms

Research

5 / 1000+ results

research MULTIPLE DEFECTS OF THE HAIR SHAFT IN NETHERTON'S DISEASE.

58 citations , November 1969 in “British Journal of Dermatology”

This report describes two patients with ichthyosis linearis circumflexa exhibiting symptoms resembling Netherton's disease, noting multiple hair shaft defects and discussing a possible connection to aminoaciduria.

research Acquired pili torti--a structural hair shaft defect in anorexia nervosa.

15 citations , March 1996 in “PubMed”

This study found that 82.3% of girls with anorexia nervosa had pili torti, an acquired hair defect, suggesting a potential link to excess vitamin A intake.

research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature

15 citations , June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study identifies KLK14 as a significant factor contributing to hair defects and skin inflammation in a mouse model of Netherton syndrome.

research Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75

6 citations , September 2015 in “Journal of Investigative Dermatology”

This study demonstrated that RNA interference targeting mutant keratin genes can effectively correct hair shaft structural defects in a mouse model by reducing mutant gene expression.

research Hair Shaft Defect in a Teenage Girl: Trichoscopy Saves the Day!

December 2020 in “Dermatology practical & conceptual”

Trichoscopy helped diagnose a teenage girl's hair loss as monilethrix.

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Community Join

5 / 1000+ results

community Why Fin/Dut Isn't Working for You GPR133: a new hairloss mechanism + Steroid Hair Loss Deep Dive

6 upvotes 1 month ago

Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.

community Hair loss research is a money grab

227 upvotes 10 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community Accelerated Hair Loss from Creatine

137 upvotes 10 months ago

Creatine may cause hair loss in some individuals, especially those on finasteride, despite no scientific link. Personal experiences suggest individual sensitivity to DHT could be a factor.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community [20M] Hair Regrowth with Minoxidil ONLY- Need Opinions

in Minoxidil 244 upvotes 1 year ago

A 20-year-old is using minoxidil for hair regrowth and considering finasteride despite concerns about side effects. Many suggest adding finasteride to maintain gains, with recommendations to start with a low dose or use a topical form to minimize side effects.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Adenosine

nucleoside used for hair regrowth stimulant properties

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

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Clinics

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82
Trichology
The Hair Loss Detective CoachStafford · US

Experts

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Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

Related Terms

Hairo Fallas