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    GlossaryAndrogen Receptor (hair loss receptors)

    protein in cells that binds male hormones to regulate genes

    The androgen receptor (AR) is a type of protein found inside cells that binds to androgens, which are male hormones like testosterone and dihydrotestosterone. This binding activates the receptor, allowing it to enter the cell nucleus and influence the expression of specific genes, playing a crucial role in the development and maintenance of male characteristics, as well as in conditions like androgenic alopecia (male pattern baldness).

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn GT20029

      research compound made to degrade androgen receptors in scalp

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      an estrogen promoting hair regrowth more commonly used in women

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

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      community Rethinking DHT and Hair Loss: Are We Targeting the Wrong Enemy?

      in Research/Science 1 month ago
      Blocking DHT is not a cure for hair loss; instead, altering how scalp follicles respond to DHT might be more effective. Current treatments like topical finasteride and minoxidil are temporary solutions, and future approaches may involve gene therapy and bioengineering to change follicle behavior.

      community Dutasteride absolutely nukes hair DHT

      in Finasteride/Dutasteride  481 upvotes 3 weeks ago
      Dutasteride significantly reduces DHT levels, potentially more effectively than finasteride, and is used to treat hair loss. Some users report side effects like reduced libido and mood changes, while others experience hair regrowth and increased testosterone.

      community 15 years of finasteride/minoxidil

      in Update  194 upvotes 1 year ago
      A user shared a 15-year experience using minoxidil and finasteride for hair loss, stating that despite never missing a dose, their hairline continued to recede slowly. Other users suggested that the hair loss might be exacerbated by the use of steroids and recommended considering other treatments like dutasteride and RU58841.

      community 8.5 month progress of min/fin/RU

      in Progress Pictures  62 upvotes 4 years ago
      The conversation discusses an 8.5-month progress of using Minoxidil, Finasteride, and RU58841 for hair loss. People are complimenting the user on the significant improvement in hair thickness.