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research Persistent sexual dysfunction and depression in finasteride users for male pattern hair loss: a serious concern or red herring?

10 citations , December 2014 in “PubMed”

This review examines reports of prolonged sexual dysfunction and depression associated with finasteride for male pattern hair loss, concluding that significant biases exist and further rigorous trials are needed to assess risks.

Faculty Opinions Recommendation of Persistent Sexual Dysfunction and Depression in Finasteride Users for Male Pattern Hair Loss: A Serious Concern or Red Herring?

research Faculty Opinions recommendation of Persistent sexual dysfunction and depression in finasteride users for male pattern hair loss: a serious concern or red herring?

December 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.

research Finasteride prescribed for hair loss consistently leads to depression. Comment on ‘Depression risk of 5-alpha reductase inhibitors: impact of active-comparator versus non-drug user control groups on risk measurement’

July 2026 in “Postgraduate Medicine”

Results are not reported in this commentary, but it discusses the influence of different control group choices—an active-comparator versus non-drug users—on measuring depression risk in studies of 5-alpha reductase inhibitors.

Knowledge, Practice, and Adverse Reactions Among Hair Dye Users: A Cross-Sectional Study

research Knowledge, practice and adverse reactions amongst Hair dye users - A cross sectional study

2 citations , September 2021 in “International Journal of Ayurvedic Medicine”

In this study, most participants began using chemical hair dyes at a young age, experiencing adverse effects, but continued due to the perceived importance of hair color.

research Prevalence and Predictors of Hair Shedding among GLP-1 Receptor Agonist Users: A Cross-Sectional Study from Saudi Arabia

January 2026 in “Skin Appendage Disorders”

This study found that hair shedding occurs in seven out of ten users of GLP-1 receptor agonists in real-world settings, a much higher prevalence than in clinical trials, which affects treatment adherence, especially among women experiencing significant weight loss.

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Community Join

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community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

494 upvotes 11 months ago

Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

community Fellow RU and other hair loss research chem users, have you seen this new rule affecting your orders?

in Chat 1 upvotes 1 year ago

The conversation discusses concerns about a new rule affecting orders of hair loss treatments like Minoxidil, finasteride, and RU58841. Users are worried about the impact on their ability to obtain these products.

community For Dutasteride Users - Do You use it Daily, or Every Other Day for Hair Loss?

5 upvotes 1 month ago

Many users take Dutasteride daily or several times a week for hair loss, with some combining it with Finasteride or Minoxidil for better results. Experiences vary, with some reporting side effects like reduced libido initially, but most find a routine that stabilizes hair loss.

community All my Finasteride users out there that take Creatine. Does it cause hair loss? What’s your experience and how much were you taking?

5 upvotes 4 years ago

Finasteride users discuss the potential impact of creatine on hair loss and libido. Some report no change, while others notice increased hair thinning, suggesting mixed experiences.

community 25M | 10 years of gradual hair loss | Minoxidil user | Looking for input on treatment optimization before HT

4 upvotes 9 months ago

A 25-year-old male with 10 years of hair loss is using minoxidil and considering adding finasteride or dutasteride, possibly with microneedling, to improve hair regrowth before a hair transplant. Community members suggest starting a DHT blocker immediately, considering oral minoxidil, and addressing low vitamin D and HDL levels.

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Learn

10 / 66 results

learn Thymosin Beta 4

What should users understand about the scientific status of Thymosin Beta 4 in hair growth therapies? Thymosin Beta 4 is not an approved treatment for hair loss and remains in early research stages.

learn Valproic acid

What should users understand about the distinction between medical research and consumer hair products involving valproic acid? Valproic acid is a prescription drug, not a cosmetic ingredient for hair loss.

learn Stem Cell Factor

Can stem cell factor be combined with other topical hair loss solutions? No published human trial has tested topical stem cell factor alongside minoxidil or other established treatments, so neither the safety nor the benefit of the combination has been established. Community users report layering these products, but that is anecdote rather than clinical evidence.

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Cetirizine

popular antihistamine showing promise for hair loss as an anti-inflammatory and prostaglandin inhibitor

learn Hair Fibers

cosmetic product that temporarily makes hair appear thicker

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn Redensyl

commercial product with a blend of mostly natural ingredients for hair regrowth

learn Adenosine

nucleoside used for hair regrowth stimulant properties

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Clinics

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All 14 clinic results →

Experts

1 / 18 results

Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas