September 2019 in “Journal of Investigative Dermatology”
This study found that polyamine levels were higher in the vertexhair than in occipital hair among patients with pattern baldness, suggesting a relation to hairloss development in the scalp's vertex region.
125 citations
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May 2007 in “Journal of The American Academy of Dermatology”
This study describes the development of the BASP classification system, providing a universal and systematic approach for classifying pattern hairloss in both men and women.
The conversation discusses hairloss treatments, focusing on the anti-androgen component CB 03 01 and its systemic absorption and safety compared to finasteride. It highlights concerns about inhibiting DHT conversion and the safety of using clascoterone for hairloss.
A 23-year-old male is experiencing diffuse hairloss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.
PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.
Creatine may cause hairloss in some individuals, especially those on finasteride, despite no scientific link. Personal experiences suggest individual sensitivity to DHT could be a factor.
A 29-year-old with hairloss (NW 3) uses microneedling, oral minoxidil, and ketoconazole shampoo. They are considering topical dutasteride after limited success with current treatments and are questioning why it's not more widely discussed.
Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.