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research 75995 Social Listening Analysis of 143,000 Online Conversations on Hair Loss Treatments: Side Effects, Satisfaction, and Discontinuation

September 2025 in “Journal of the American Academy of Dermatology”

This study explores patients' perceptions of hair loss treatments, specifically oral minoxidil, topical minoxidil, and oral finasteride, building on existing clinical research.

research Hair Loss as a Side Effect of Quetiapine: A Clinical Case Report

January 2025 in “Scholars Journal of Medical Case Reports”

In this study, a 37-year-old Moroccan man experienced hair loss after two months of quetiapine treatment for major depressive disorder, which resolved after discontinuation, highlighting the need for awareness of this potential rare side effect.

research Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss

185 citations , March 2011 in “The Journal of Sexual Medicine”

This study found that 94% of healthy men reported low libido and 92% reported erectile dysfunction as persistent sexual side effects after using finasteride for male pattern hair loss, with these effects lasting on average 40 months post-discontinuation.

research Hair Loss Is a Potential Side Effect of Novel Oral Anticoagulants – Findings From the Dresden Noac Registry (NCT01588119)

8 citations , November 2012 in “Blood”

This study observed that the incidence of hair loss as a spontaneously reported side effect of novel oral anticoagulant therapy is approximately 4.4 per 100 patient years.

Regenerative Medicine to Reduce the Side Effects of Radiotherapy Causing Skin Cancer, Fibrosis, Neuropathic Pain, and Hair Loss

research Regenerative Medicine to Reduce the Side Effects from Radiotherapy Causing Skin Cancer, Fibrosis, Neuropathic Pain and Hair Loss

1 citations , January 2021 in “Journal of Cancer Therapy”

This article reviews regenerative medicine strategies, such as stem cells and plant polyphenols, for mitigating radiotherapy side effects but does not present new clinical findings, calling for further investigation.

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Learn

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learn Setipiprant

What side effects or limitations have been reported with Setipiprant use in hair loss research? In the one published hair-loss trial (DuBois 2021, 169 men, 24 weeks), setipiprant produced no significant hair regrowth over placebo. Treatment-related side effects — mostly mild headaches, stomach upset and fatigue — were reported in about a quarter of the setipiprant group versus just over twelve percent on placebo, and no serious events were attributed to the drug. It is an unapproved, experimental compound with no long-term safety data.

learn Hair Transplant

What are the risks and side effects of a hair transplant? Common risks include swelling, redness, infection, scarring, and temporary hair loss.
What are the risks and side effects of FUE hair transplants? Providers describe most FUE side effects, such as swelling, redness, numbness and shock loss, as temporary, but FUE is surgery and the same sources report pain, infection, folliculitis and small permanent donor-site scars. Longer-lasting problems, including visible donor-area thinning or poor graft growth, are possible and are not covered by this provider survey.
What precautions should be taken after a hair transplant? Clinics commonly advise avoiding strenuous activity, smoking, alcohol, direct sun and touching the grafts while the scalp heals. Any change to a prescribed medicine, including blood thinners, should be agreed with the doctor who prescribed it.

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Low Level Laser Therapy

laser therapy for anti-inflammatory and likely insignificant hair regrowth effects

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Saw Palmetto

a natural and far less effective alternative to Finasteride

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Community Join

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community I have tried every hairloss option between shaving and wigs. Considering retrying fin because depression medication also has sexual side effects and hairloss has driven me to almost need them. Every hairloss option I have tried has a "dealbreaker" caveat and so I am forced to choose one of the below

4 upvotes 10 years ago

The user is struggling with hair loss and has tried treatments like finasteride, minoxidil, and hair systems, each with drawbacks. They are considering retrying finasteride before a hair transplant and are advised to seek therapy for mental health support.

community Hair loss mental effect is so bad

in Satire 177 upvotes 1 year ago

Hair loss negatively affects mental health, causing anxiety and depression. Minoxidil and finasteride are discussed as treatments, but side effects and mental health concerns remain.

community How effective is RU58841 in hairloss products?

6 upvotes 7 months ago

RU58841 is used for hair loss, with mixed effectiveness and potential side effects like heart issues. Some users find it effective, while others see no results; alternatives like finasteride and dutasteride are also mentioned.

community Mesotherapy Dutasteride Reverses Hair Loss. Most effective treatment we have in reducing scalp DHT

5 upvotes 2 years ago

Mesotherapy Dutasteride is considered highly effective for reducing scalp DHT and potentially reversing hair loss. However, one user reported systemic side effects and no improvement in hair loss.

community Hypothetically, if estradiol has been a "cure" for hair loss, could one apply estradiol topically and just take an estrogen blocker and/or testosterone to offset the systematic effects?

8 upvotes 1 year ago

Topical estradiol may help with hair loss but can have systemic effects, like reduced testosterone production. Using estrogen blockers can have negative side effects, such as joint pain and reduced sex drive.

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Clinics

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Experts

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Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas