45 citations
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March 2010 in “Journal der Deutschen Dermatologischen Gesellschaft”
This article discusses methods for diagnosing and managing diffuse hairloss and reports no new results; the authors emphasize systematic evaluation and the importance of psychological support.
5 citations
,
April 2018 in “Journal of Dermatological Science”
This study found that the E2-ANGPT2 pathway is involved in hair follicle regulation and that ANGPT2 treatment increased hair density in modeled female pattern hairloss, suggesting potential therapeutic use.
This review discusses both conventional and new pharmaceutical treatments for hairloss, as well as various natural and herbal remedies, but reports no new clinical results.
November 2020 in “Journal of The American Academy of Dermatology”
This study reported that using plain bottles instead of commercial kits for extracting platelet-rich plasma may be an effective method for treating hairloss.
This research found that Foxc1 transcription factor and COL17A1 are critical in regulating quiescence and hair thinning in hair follicle stem cells, with aging-related DNA damage leading to hairloss.
Hairloss may be linked to blood flow issues, but DHT is considered the main cause. Treatments used include finasteride, RU58841, minoxidil, vitamin D3, microneedling, and dutasteride, but hairloss persists.
Hairloss negatively affects mental health, causing anxiety and depression. Minoxidil and finasteride are discussed as treatments, but side effects and mental health concerns remain.
Blocking the Mitochondrial pyruvate carrier and using aldose reductase inhibitors like Indian gooseberry and berberine may help with hair growth. Magnesium can also be added to increase NADPH.
Bryan Johnson uses topical dutasteride, minoxidil, and microneedling for hairloss. Users discuss treatment effectiveness and side effects, debating topical versus oral dutasteride efficacy.
A 47-year-old male experienced significant hairloss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hairloss.