17 citations
,
January 2013 in “Journal of Cutaneous Pathology”
This study reported that the concept of the onychodermis, defined by CD10 expression, is present in the developing nail organ and may play a role in nail plate formation.
This article reviews the occurrence of ectopic sebaceous glands in hairfollicle matrix during hair embryogenesis and reports no new clinical results, indicating unknown pathogenesis and clinical implications.
This review emphasizes the importance of understanding hairfollicleembryology, anatomy, and the hair cycle to effectively diagnose and treat hair disorders like alopecia.
13 citations
,
December 2020 in “Dermatologic Therapy”
This review discusses the embryology, structure, and function of sebaceous glands and their involvement in skin disorders but reports no novel findings.
Hairfollicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.
Hairfollicles are mostly dormant but can be reactivated with treatments like minoxidil, finasteride, and microneedling. A new drug, PP405, shows promise for hair regrowth but may not be available until 2027-2028.
The conversation discusses using hairfollicle dermal papilla exosomes for hair loss treatment. It inquires about purchasing options for this treatment.
Hairfollicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.
Hairfollicle regeneration through stem cell rearrangement is discussed, focusing on bioengineered cellular structures rather than traditional hair transplants. Treatments mentioned include Minoxidil, finasteride, and RU58841.
Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.