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research Data_Sheet_1_Disruption of Hars2 in Cochlear Hair Cells Causes Progressive Mitochondrial Dysfunction and Hearing Loss in Mice.docx

December 2021 in “OPAL (Open@LaTrobe) (La Trobe University)”

This study found that knocking out the Hars2 gene in mouse cochlear hair cells led to mitochondrial dysfunction and ROS stress, resulting in progressive hearing loss and differential effects on inner and outer hair cells.

research 329 In vitro co-culture models of merkel cell-neurite complex in touch domes

October 2021 in “Journal of Investigative Dermatology”

In this research, investigators used in vitro models to study the Merkel cell-neurite complex and reported that mechanical stimulation, similar to gentle touch, can induce molecular changes that are potentially relevant to hair growth, thus contributing to the understanding of its underlying mechanisms.

research Melatonin induces a stimulatory action on the scrotal skin components of Soay ram in the non-breeding season

13 citations , June 2020 in “Scientific reports”

In this study, melatonin administration enhanced various cellular and structural features of the scrotal skin in Soay rams, including increased thickness, cell count, and gland activity.

research In Vitro differentiation of hair-follicle bulge stem cells into synaptophysin-expressing neurons: a potential new approach for neuro-regeneration

November 2024 in “Human Cell”

This study found that treating rat whisker follicle stem cells with retinoic acid and epidermal growth factor induced them to express synaptophysin, a marker of mature neurons, although there was a reduction in other neural markers, suggesting potential for neuro-regeneration applications.

research Hair cell loss – cause or consequence of hearing loss?

April 2026 in “Frontiers in Cell and Developmental Biology”

This literature review suggests that hair cell loss in hearing loss is often secondary to preceding morphological and functional defects in hair cells, indicating that interventions should focus on hearing preservation before significant hair cell loss occurs.

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Community Join

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community Has anyone here actually undergone experimental (grey market) hair cell therapy/follicle cloning?

7 upvotes 5 months ago

Hair cell therapy and follicle cloning are still in experimental stages, with treatments like hair multiplication and regenerative hair therapy being marketed but not yet proven to create unlimited new follicles. There is skepticism about the effectiveness and legitimacy of these treatments, with some considering them scams.

community Stem cell hair transplant? Any progress?

4 upvotes 1 year ago

Stem cell hair transplants are not yet viable, and users suggest traditional treatments like Minoxidil, finasteride, and hair transplants. Some mention verteporfin but note its alcohol restrictions.

community Stem-cell hair transplants! 20k lab grown grafts from one single graft

50 upvotes 2 years ago

Stem-cell hair transplants could potentially create thousands of grafts from a single donor graft, offering a solution for hair loss with DHT-resistant hair. Companies like Stemson Therapeutics and OrganTech are working on this technology, which may become available in the future, possibly reducing the cost and making it widely accessible.

community Any experience with stem cell hair transplants?

26 upvotes 3 years ago

Stem cell hair transplants use stem cells from fat tissue to reactivate inactive hair follicles, but results are inconsistent and not widely shared. Traditional treatments like finasteride and minoxidil often show better results.

community Thoughts on STEM cell hair transplants?

in Transplants 4 upvotes 3 years ago

Stem cell hair transplants are not FDA approved and remain theoretical, with concerns about effectiveness and safety. Current treatments like finasteride and minoxidil are still the main options, while hair cloning and new drug cures are likely years away.

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Learn

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learn Stem Cell Factor

When should you expect visible hair improvement from stem cell factor treatments? Visible hair improvement from stem cell factor treatments may take several months.
What is stem cell factor and why is it used in hair growth treatments? Stem cell factor promotes hair growth by signaling cell survival and division.
How does stem cell factor help activate dormant hair follicles? Stem cell factor activates dormant hair follicles by signaling through the c-Kit receptor.
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learn Hair Transplant

Can a hair transplant be combined with other treatments? Clinics commonly say a transplant is combined with other treatments, most often minoxidil, finasteride or PRP, but the evidence behind each add-on differs. Some of the add-ons offered, such as stem-cell or exosome products, are not approved treatments for hair loss.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Estradiol

an estrogen promoting hair regrowth more commonly used in women

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Clinics

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All 64 clinic results →

Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas