research Application of histamine receptors H2R, H3R and H4R, but not H1R, in dermatology
This review explores the roles of histamine receptors H2R, H3R, and H4R in treating various dermatoses but reports no new clinical outcomes.
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5 / 399 resultsresearch Repurposing of H1-receptor antagonists (levo)cetirizine, (des)loratadine, and fexofenadine as a case study for systematic analysis of trials on clinicaltrials.gov using semi-automated processes with custom-coded software
Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.
research Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia
This review discusses recent developments in α1-adrenoceptor antagonists and 5α-reductase inhibitors for treating benign prostatic hyperplasia, reporting no new clinical results while identifying potential areas for future drug development.
research The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes through the β-Arrestin Pathway
This study found that activation of delta-opioid receptors in keratinocytes may delay the expression of the PER2 gene, suggesting a possible link to cancer development through circadian rhythm disruption.
research Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation
In this study, ebastine significantly increased the proliferation of human follicle dermal papilla cells and may contribute to hair regrowth by activating the ERK signaling pathway.
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