June 2025 in “JURNAL BIOLOGI TROPIS” This review found that secondary metabolites from herbal plants, including flavonoids and alkaloids, show potential in promoting hair growth through mechanisms like anagen phase prolongation and enzyme inhibition, but more clinical trials are needed to confirm their efficacy.
December 2024 in “PLoS ONE” In this study, researchers evaluated male-pattern hair loss treatments using RNA and microRNA expression profiling in 91 male participants, identifying 52 differentially expressed genes and suggesting a potential role for personalized treatment based on genetic analysis to monitor and predict treatment efficacy and compliance.
54 citations
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February 1994 in “Journal of Investigative Dermatology”
17 citations
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August 2007 in “Bioorganic & Medicinal Chemistry Letters” This study found that a specific amino-pyridine compound showed potent androgen receptor antagonist activity, stimulating hair growth in mice and reducing sebum production in a hamster model.
14 citations
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August 2007 in “Bioorganic & Medicinal Chemistry Letters” This study reported that the compound (1R, 2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile effectively stimulated hair growth in mice and reduced sebum production in hamsters.