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research Evaluation of the Effect of Plant Mixture Ethanol Extracts Containing Biota orientalis L. Extract on Suppression of Sebum in Cultured Sebocytes and on Stimulation of Growth of Keratinocytes Co-cultured with Hair Papilla Cells

4 citations , August 2017 in “Cosmetics”

This study observed that Biota orientalis L. leaf extract may promote hair growth and suppress sebum production in human cells, suggesting potential benefits for hair restoration.

research Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice

9 citations , July 2021 in “Frontiers in Pharmacology”

This study found that intradermal injection of cholesterol-modified siRNA targeting FGF5 or FGF18, or topical application of FGF18-targeted siRNA, effectively influenced hair follicle cycles in mice, suggesting potential benefits for alopecia management.

research Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin

7 citations , March 2022 in “International Journal of Molecular Sciences”

This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.

research OsCSLD1 Mediates NH4+-Dependent Root Hair Growth Suppression and AMT1;2 Expression in Rice (Oryza sativa L.)

1 citations , December 2022 in “Plants”

This study suggests that CSLD1 is key to nitrogen-dependent root hair elongation and regulation of AMT1;2 expression in rice roots.

research Cyclosporine A increases hair follicle growth by suppressing apoptosis-inducing factor nuclear translocation: a new mechanism

9 citations , January 2015 in “Fundamental & clinical pharmacology”

This study found that cyclosporine A's enhancement of hair growth in mice is partly due to its ability to block the nuclear translocation of apoptosis-inducing factor, slowing the hair follicle transition to the catagen phase.

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Community Join

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community Research: Minoxidil grows hair by suppressing androgen activity (DHT) in hair follicles.

43 upvotes 6 years ago

Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.

community Is it effective to make microneedling without minoxidil?

in Chat 31 upvotes 10 months ago

Microneedling can be effective for hair growth, but it is more effective when combined with minoxidil. Finasteride or other DHT suppressants are necessary to prevent hair loss due to male pattern baldness.

community Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)

in Research 598 upvotes 1 year ago

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

community Wouldn’t this nuclear stack make it almost impossible to lose hair?

67 upvotes 1 year ago

The conversation discusses a hair loss treatment regimen involving dutasteride, pyrilutamide, oral minoxidil, and microneedling, with the aim of suppressing DHT and stimulating hair growth. Users debate the effectiveness and potential side effects of these treatments, noting that individual results may vary and that no treatment is foolproof.

community Beard growth stunted due to DHT blockers

in Finasteride/Dutasteride 23 upvotes 7 months ago

DHT blockers like dutasteride can reduce beard thickness while improving scalp hair. Using minoxidil on the beard may help maintain its thickness.

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Learn

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learn Stem Cell Factor

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Epidermal Growth Factor

learn Vascular Endothelial Growth Factor

learn Caffeine

Does caffeine stimulate hair growth or only slow hair loss? Caffeine stimulates hair follicles in laboratory cultures, and one open-label trial in 210 men found a 0.2% caffeine topical non-inferior to minoxidil 5% on an anagen-ratio endpoint; there is no placebo-controlled evidence that it regrows hair, and none at all in alopecia areata or telogen effluvium.

learn Lavender

Does lavender promote hair growth or just soothe an irritated scalp? Lavender may promote hair growth and soothe an irritated scalp.

learn Bimatoprost

Can a lash-growth serum like bimatoprost actually work for your scalp? Bimatoprost (Latisse) is approved for eyelashes, not the scalp; two Allergan phase 2 trials in men with androgenetic alopecia posted results to ClinicalTrials.gov but were never published in a peer-reviewed journal, so scalp use remains off-label and experimental.

learn Dexpanthenol

Does dexpanthenol promote hair growth? Dexpanthenol improves hair moisture and strength but does not directly promote hair growth.

learn horsetail extract

How does horsetail extract support hair growth — is it the silica, the antioxidants, or both? Horsetail extract supports hair growth primarily through its silica content.

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