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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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learn Thymosin Beta 4
learn Hair Multiplication
extract, clone, and reinsert your own hair cells
learn Stemoxydine
chemical from L'Oreal that encourages hair to enter growth phase
Research
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research Clinical Relevance of Hair Microscopy in Alopecia
Hair microscopy is useful for diagnosing certain hair loss conditions but has limitations and must be interpreted carefully.
research A Topical Botanical Lotion Increases and Remodels Scalp Collagen Content Through Longer Anagen Phase, Opening New Perspectives
A botanical lotion can increase scalp collagen and extend hair growth phase, potentially improving hair thinning issues.
research A New Model of Blood Vessel Remodeling
Hair follicles influence blood vessels during hair growth, suggesting potential treatments for hair growth issues.
research Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway
Applying a special compound can promote hair growth without harmful side effects.
research Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Trial
Sandalore, a synthetic scent, was found to reduce hair loss and improve hair growth in women with hair shedding issues.
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5 / 1000+ resultscommunity TDM-105795 phase 2 results are in!
TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.
community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth
PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.
community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.
Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.
community Why don't Minoxidil regenerated hairs become terminal on the head?
Minoxidil helps hair growth by increasing blood flow and prolonging the growth phase, but it doesn't address the root cause of hair loss, such as DHT sensitivity. Finasteride can help maintain some gains by blocking DHT, but stopping Minoxidil often leads to hair loss because the new hairs are dependent on it.
community Surprisingly thorough study on He-Shou-Wu/Fo Ti
He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.