research Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis
Trichohyalin is also found in the outer layers of normal human skin.
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5 / 1000+ results research Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour
The study used immunohistochemistry to examine the distribution of various keratins in the epidermis of the Malayan pangolin (Manis javanica), revealing region-specific differences in keratin expression. Pan-keratin showed varying intensities, with strong reactions in the abdominal epidermis's outer layers and positive reactions in the dorsolateral epidermis's vital layers. Specific keratins like CK1 were present in all epidermal layers except the ventral stratum corneum, while CK5, 6, 9, and 10 were limited to the soft ventral epidermis. Hair keratins AE13 and AE14 showed distinct patterns, with AE13 in the dorsal granular layer and AE14 in the abdominal stratum basale and hair follicle root sheath cells. These findings were discussed in the context of the evolutionary development of the pangolin's dorsal scales, suggesting an origin from the tail root extending towards the head.
research Distinguishing Histopathologic Features of Acantholytic Dermatoses and the Pattern of Acantholytic Hypergranulosis
Different skin diseases show unique patterns of skin cell separation, cell death, and granular layer changes.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Sjogren-Larsson Syndrome: Case Study of a 9-Year-Old Boy
A boy with Sjogren-Larsson syndrome has skin and muscle symptoms due to a specific enzyme deficiency.
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4 / 4 resultscommunity The truth about Dutasteride (w/ sources)
The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.
community A guide to "Am I balding or not?" - How to Track your Hair Regrowth/Loss
The conversation provides advice on how to track hair loss or regrowth, emphasizing the importance of taking consistent photos and keeping a log of treatments like minoxidil and finasteride. It also suggests using scalp cameras and comparing photos side by side for accurate progress assessment.
community My journey from Norwood 3.5/4 to Norwood 0
A user's hair regrowth journey involved a hair transplant and using RU58841, finasteride, and minoxidil, with side effects managed by other medications.
community Molecule PP405: A Research Team Backed By Google Ventures Has Discovered One Of The Most Promising Solutions For Hair Loss To Date
PP405 is a promising new treatment for hair loss that activates dormant stem cells in hair follicles, potentially bypassing the effects of DHT. It is currently in phase 2 trials and could be available between 2027 and 2030, but it is not considered a definitive cure.