research Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia?
This study found sebaceous gland atrophy and altered gene expression in psoriatic skin lesions, which may relate to the observed hair loss in these areas.
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research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
In this study, topical application of the SCD1 inhibitor XEN103 significantly reduced sebaceous gland size and number in mouse skin, suggesting potential local therapeutic effects for acne treatment without systemic side effects.
research Adenohypophysitis Associated with Sebaceous Gland Atrophy in a Dog
In this case report, a 9-year-old Samoyed dog with a history of dermatitis showed symptoms compatible with chronic sebaceous adenitis, marked by the absence of sebaceous glands and non-granulomatous skin infiltration.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
This study found that prolonged inhibition of DGAT1 in mice and dogs led to atrophy of sebaceous glands, with mice also experiencing alopecia, suggesting potential skin-related risks for humans using DGAT1 inhibitors.
research Sebaceous gland atrophy due to seborrheic dermatitis in a patient with alopecia: A potential pitfall
In this case report, the authors identified that sebaceous gland atrophy, traditionally associated with psoriatic or drug-induced alopecia, can also appear in seborrheic dermatitis, complicating the histopathological evaluation of alopecia biopsies and emphasizing the need to consider seborrheic dermatitis in differential diagnoses.
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5 / 1000+ resultscommunity If you were on finasteride, but experiencing negative symptoms and didn’t know about PFS, would you want someone to tell you?
Finasteride users discuss potential side effects, including Post Finasteride Syndrome (PFS), with varying opinions on its legitimacy and impact. Some users report side effects like changes in semen consistency and reduced pre-ejaculate, while others emphasize the rarity and reversibility of side effects.
community Severe dry eye: finasteride vs dutasteride
Woman uses antiandrogens for hair thinning prevention, experiences severe dry eye with finasteride. Asks if dutasteride could be better despite potential for worse dry eye.
community Microneedling must reach the stem cells in the upper hair shaft
Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.
community 20MTF Results on the crown from 1 year on estrogen injections
Estrogen injections significantly improved hair growth, particularly on the crown, after stopping finasteride. Monotherapy with estrogen led to hairline improvement, but also caused sterility and potential feminization effects.
community Low-Dose Oral Minoxidil Does Not Significantly Affect BP
Low-dose oral minoxidil is used for hair loss and does not significantly affect blood pressure but may increase heart rate and cause hypotensive symptoms. Some users experience side effects like palpitations and shortness of breath, while others find it effective; topical minoxidil with tretinoin is also considered.
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