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research Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation

29 citations , December 2016 in “The EMBO Journal”

This study found that the transcription factor Gata6 plays a crucial role in adult mouse hair follicle regeneration by promoting the renewal and preventing DNA damage of rapidly proliferating progenitor cells.

research REV7: a small but mighty regulator of genome maintenance and cancer development

1 citations , January 2025 in “Frontiers in Oncology”

This review highlights REV7's crucial roles in maintaining genome stability, its implication in several cancers, and its association with poor prognoses and treatment resistance, while also noting that REV7 suppression may improve chemotherapy sensitivity.

research Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne

43 citations , November 2018 in “Nature Communications”

This genome-wide association study identified 20 genetic signals at 15 risk loci related to severe acne, revealing new insights into its genetic predisposition, particularly affecting skin structure and maintenance.

research The Genetics of Acne

July 2025 in “Annals of Human Genetics”

This review examines the genetics of acne vulgaris, concluding that stem/progenitor cell maintenance and cellular migration are key processes in its pathogenesis, potentially shifting future treatment strategies beyond traditional antibiotics and retinoids, which have notable side effects.

research Replicative stress, stem cells and aging

70 citations , March 2008 in “Mechanisms of Ageing and Development”

This review discusses genome maintenance mechanisms critical for preventing age-related diseases by preserving stem and progenitor cell potential, but reports no new empirical findings.

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community The end of minoxidil and fin/dut regime

106 upvotes 6 months ago

New hair loss treatments like GT20029 and PP405 could potentially replace minoxidil and finasteride, offering better results with fewer side effects. However, current treatments like finasteride and minoxidil are still effective for many, despite concerns about side effects.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community How is there zero improvement with finding the cure?

in Research/Science 245 upvotes 7 months ago

Hair loss treatments have not advanced since 2018, with finasteride, minoxidil, and RU58841 still being the main options. A permanent cure is unlikely due to the profitability of ongoing treatments.

community How many of you guys take creatine and is on finasteride ? Any issues ?

17 upvotes 1 year ago

Some users report no issues with hair loss while taking creatine and finasteride, while others experience shedding and attribute it to creatine. The effects of creatine on hair loss appear to vary, with some individuals being more sensitive to DHT increases.

community How do athletes maintain their hair transplants? Or do they not?

in Transplants 57 upvotes 1 year ago

Athletes often use finasteride to maintain hair transplants, but some avoid it due to potential hormonal effects. Notable examples include Mo Salah and Conor McGregor, while LeBron James has had multiple procedures with varying success.

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Clinics

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Hair Loss Treatments
Scalp Care/Scalp Maintenance-Hair farmTaipei · TW

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