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Glossary Genetic Testing

analyzing DNA to identify genetic mutations or predispositions

Genetic testing, also known as DNA testing or genetic screening, involves analyzing an individual's DNA to identify changes or mutations that may indicate a risk for certain genetic disorders or diseases. This process can help diagnose conditions, guide treatment decisions, and inform individuals about their genetic predispositions, including those related to hair loss and alopecia.

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Research

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Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing

research Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing

11 citations , November 2012 in “Seminars in Cutaneous Medicine and Surgery”

This review summarizes current understanding and genetic insights into androgenetic alopecia, female pattern hair loss, and alopecia areata, noting the potential future role of molecular diagnostics, but it reports no new clinical results.

research For early diagnosis of young patients with Werner syndrome: Indication for genetic testing

February 2025 in “Geriatrics and gerontology international/Geriatrics & gerontology international”

This study found that cataracts, hair changes, short stature, and low bodyweight are key indicators for diagnosing Werner syndrome in patients under 30, differing from older age group symptoms.

Navigating Diagnostic Uncertainty: Frontal Fibrosing Alopecia Versus Keratosis Pilaris Atrophicans Faciei With Genetic Testing Insights

research Navigating Diagnostic Uncertainty: Frontal Fibrosing Alopecia Versus Keratosis Pilaris Atrophicans Faciei With Genetic Testing Insights

April 2024 in “Curēus”

In this case study, a 36-year-old male with symptoms of keratosis pilaris atrophicans faciei and frontal fibrosing alopecia tested negative for a specific mutation, highlighting genetic testing's potential to improve diagnosis and treatment outcomes in these similar conditions.

research Case Study: Hereditary Cancer Genetic Testing in Unaffected Patients May Allow for Early Intervention and Aggressive Management

October 2014 in “Journal of Minimally Invasive Gynecology”

Genetic testing for cancer risk can lead to early and life-saving treatments in people without symptoms.

research Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation

50 citations , May 2018 in “International journal of cardiology”

This study found associations between genetic predictors of increased testosterone and cardiovascular risk factors, but the implications for testosterone supplementation are unclear due to uncertainties in genetic variant functions.

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Community Join

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community DNA Testing by Roots by Genetic Arts

4 upvotes 2 years ago

A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

community Is trichogram a good thing for testing genetic hair loss

2 upvotes 6 months ago

A dermatologist checked for hereditary hair loss using blood tests and plans to perform a trichogram. The user had slightly low Vitamin D3 levels, and the trichogram may help confirm androgenetic alopecia.

community Testosterone in Reference Range Doesn't Cause Hair Loss

52 upvotes 2 years ago

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

community Pre Finasteride Treatment, is testing for free DHT necessary?

4 upvotes 3 years ago

The conversation is about whether testing for free DHT is necessary before starting Finasteride for hair loss, despite having other hormone tests available. One person suggests that genetic response to DHT is more important than DHT levels and advises starting Finasteride without the free DHT test.

community Dutasteride Vs. Testosterone, who wins?

in Finasteride/Dutasteride 58 upvotes 2 years ago

The conversation discusses whether 2.5mg of dutasteride or 200mg of testosterone weekly is more influential in preventing hair loss, with various personal experiences indicating that the effectiveness is dependent on the individual's genetic profile. Some users report that dutasteride is likely to be more effective at the given doses.

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Learn

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learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Thymosin Beta 4

learn Vitamin B1

Thinning hair over time? It might not just be genetics: lack of B1 and B2 could be silently working against you. There is no verified human trial showing that B1 or B2 deficiency causes thinning hair or that correcting it regrows hair; a 2019 review concludes the role of micronutrients in hair loss is real but unclear and still needs controlled trials.

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