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Glossary Gene Expression

process where genetic information directs protein or RNA synthesis

Gene expression is the process by which information from a gene is used to synthesize functional gene products, such as proteins or RNA. This process involves two main stages: transcription, where the DNA sequence of a gene is copied into mRNA, and translation, where the mRNA is used as a template to build proteins. Gene expression is tightly regulated to ensure that the right genes are expressed at the right times and in the right amounts, which is crucial for normal development, cellular function, and response to environmental changes.

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Research

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research Change in Hair Growth-related Gene Expression Profile in Human Isolated Hair Follicles Induced by 5-alpha Reductase Inhibitors, Dutasteride and Finasteride, in the Presence of Testosterone

January 2019

This study suggests that 5AR inhibitors may reverse decreased expression of growth factor genes in human hair follicles under testosterone stimulation, indicating involvement of type I 5AR in hair growth.

research Changes in expression of the neuropeptide Y Y₁ receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery

12 citations , September 2002 in “Journal of Neurochemistry”

This study found that changes in the brain concentrations of neuroactive steroids during pregnancy are linked to increased Y 1 receptor gene expression in the medial amygdala of transgenic mice.

research Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors – dutasteride and finasteride – in the presence of testosterone

1 citations , June 2021 in “Singapore Medical Journal”

This study suggests that type I 5-alpha reductase may also play a role in hair growth, with dutasteride potentially being more potent than finasteride in modulating key hair growth gene expressions.

research Age and Sex-Related Changes to Gene Expression in the Mouse Spinal Cord

8 citations , July 2019 in “Journal of Molecular Neuroscience”

research Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle

149 citations , June 2010 in “The FASEB journal”

In this study, miR-31 was found to play a significant role in hair cycle regulation in mice by controlling key gene expressions involved in hair growth and differentiation.

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Community Join

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community Do you think people of previous generations had better hair? What changed?

2171 upvotes 1 year ago

Hair loss is less common now due to accessible treatments like finasteride, minoxidil, and hair transplants. Improved hair care, skincare, and lifestyle changes contribute to people looking younger today.

community Is Topical Dutasteride best for preventative loss?

7 upvotes 3 years ago

The user is considering using topical dutasteride to prevent hair loss progression from Norwood 1 to Norwood 2 at age 25, and is concerned about the long-term effectiveness and potential shedding from the treatment. They are currently using a shampoo with caffeine, rosemary, and saw palmetto, and have noticed hair thinning and changes since age 20.

community 200 days on dut + min, what do you think?

599 upvotes 11 months ago

The user reports significant hair regrowth after 200 days using dutasteride and minoxidil, attributing changes to hair dye. Others doubt the authenticity and discuss treatment effectiveness and side effects.

community 2000 beard graft extracted with no visible scar

213 upvotes 1 year ago

A user shared their experience with a beard-to-scalp hair transplant, noting no visible scars and improved hair density using finasteride and minoxidil. The conversation discusses the differences between beard and scalp hair, potential changes in hair texture, and the use of beard hair for increased scalp coverage.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 58 upvotes 1 year ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

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Learn

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learn Valproic acid

Anti-seizure and mood-stabilising drug

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Thymosin Beta 4

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