4 citations
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June 2005 in “Andrology” This case report describes a woman with severe hyperandrogenism due to ovarian tumors, where surgical removal led to dramatic improvement in her diabetes control and reduced insulin requirements.
March 2010 in “Ejc Supplements” This study highlights a paradox where valproic acid, known for causing hair loss, may also promote hair growth when applied topically.
17 citations
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May 2012 in “Clinical Endocrinology” This study found that surgical normalization of testosterone in hyperandrogenic women with ovarian androgen-secreting tumors did not significantly change body weight or insulin sensitivity after 12 months.
This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.
14 citations
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August 2021 in “Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy” This research discusses the potential antitumor effects of metformin, a common diabetes medication, noting its controversial influence on different malignant tumors and its uncertain mechanisms. Understanding these effects on tumors may aid in the development of new cancer treatments.