learn Tretinoin
the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil
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5 / 12 resultslearn Vascular Endothelial Growth Factor
learn Overview
learn HMI-115
much-hyped research compound targeting prolactin receptor in scalp
learn GHK-Cu
a copper peptide showing promise in both regrowth and reversing gray hair
Research
5 / 1000+ resultsresearch Fractional Microporation-Guided Delivery of Nanoencapsulated Drugs for Enhanced Cutaneous and Follicular Absorption: A Comparison of Ablative Laser and Radiofrequency Microneedling
research Methods for Quantifying Intrafollicular Drug Delivery: A Critical Appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research Impact of Ester Promoieties on Transdermal Delivery of Ketorolac
Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
research The Role of Hair Follicles in the Percutaneous Absorption of Caffeine
Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
research Follicular and Percutaneous Penetration Pathways of Topically Applied Minoxidil Foam
Minoxidil foam enters hair follicles and skin for hair growth.
Community Join
5 / 296 resultscommunity Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)
Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.
community I literally can’t find any evidence of sulfotransferase being upregulated by microneedling or retinoids like tretinoin
Microneedling and tretinoin may enhance minoxidil absorption for hair loss, but evidence on their effectiveness is limited. Iron supplements and broccoli sprouts are suggested for enzyme activation, but their impact on hair is unclear.
community Microneedling at .25 everyday before applying Min
Daily microneedling at 0.25mm before applying minoxidil is debated, with some suggesting weekly microneedling is safer and more effective. Concerns include potential skin damage and systemic absorption, while alternatives like tretinoin are considered safer for enhancing minoxidil absorption.
community Is microneedling + minoxidil better than oral minoxidil
Oral minoxidil is considered more effective for hair regrowth than topical minoxidil, but it carries higher risks. Combining microneedling with topical minoxidil can enhance absorption, but oral minoxidil with microneedling shows significant results.
community Clearing the air on how non-surgical treatments really work
Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.