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research Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial

11 citations , October 2021 in “Journal of The European Academy of Dermatology and Venereology”

This study found that topical finasteride significantly increased hair count in men with androgenetic alopecia compared to placebo while maintaining similar efficacy to oral finasteride but with lower systemic exposure and a reduced impact on serum DHT levels, potentially minimizing sexual side effects.

Efficacy and Safety of Topical Finasteride Spray Solution in the Treatment of Chinese Men with Androgenetic Alopecia: A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study

research Efficacy and safety of topical finasteride spray solution in the treatment of Chinese men with androgenetic alopecia: A phase III, multicenter, randomized, double-blind, placebo-controlled study

March 2025 in “Chinese Medical Journal”

This randomized, double-blind, placebo-controlled phase III trial found that a 24-week treatment with topical finasteride significantly increased hair growth and was well-tolerated in Chinese men with androgenetic alopecia compared to placebo.

research Topical finasteride 0.25% in HPCH spray for androgenetic alopecia: a single-center retrospective study

July 2026 in “Archives of Dermatological Research”

In this study, topical finasteride showed mild-to-moderate improvement in androgenetic alopecia among a cohort in Saudi Arabia, with combination therapy outperforming monotherapy. Adverse events were rare. The study highlights the need for prospective trials to clarify finasteride's standalone effects.

Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

research Quantitative analysis of finasteride tablets dissolution content with non-isotopically labeled internal standard by paper spray ionization mass spectrometry

2 citations , September 2018 in “Journal of Separation Science”

This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.

Self-Microemulsifying Systems of Finasteride with Enhanced Oral Bioavailability: Multivariate Statistical Evaluation, Characterization, Spray-Drying and In Vivo Studies in Human Volunteers

research Self-microemulsifying systems of Finasteride with enhanced oral bioavailability: multivariate statistical evaluation, characterization, spray-drying and in vivo studies in human volunteers

39 citations , November 2015 in “Nanomedicine”

This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.

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community New FIN/Min spray available in the UK (includes Tretinoin!)

in Finasteride/Dutasteride 7 upvotes 1 year ago

A new hair growth spray in the UK contains finasteride 0.3%, minoxidil 5%, and tretinoin 0.01%, but some users find the finasteride concentration too high. Another brand offers a similar spray with a lower finasteride dose at a cheaper price, and some users report scalp irritation from the new spray.

community Fin/Min/Ketoconazole/Biotin Spray, 9 months results

in Progress Pictures 48 upvotes 1 year ago

The user shared 9-month results using a 4-in-1 spray containing finasteride, minoxidil, ketoconazole, and biotin, along with lifestyle changes like jogging, quitting smoking, and using collagen supplements. They also incorporated dermastamping, dermarolling, and various oils into their routine, reporting positive hair regrowth.

community Tried Min+Fin spray for 6 months, with 9 months or Min alone- I'm pretty sure I'm balder than ever. I think I might be beyond saving at this point... Any Hail-Mary products I should go for? Does anyone have any insights on hair transplants? I was thinking maybe FUE.

4 upvotes 1 year ago

The user has been using Minoxidil and a Minoxidil + Finasteride spray for hair loss with no progress and is considering trying dutasteride or a hair transplant, specifically FUE. They are concerned about side effects and the potential risks of surgery.

community Hims topical min/fin spray vs serum

9 upvotes 2 years ago

The conversation is about someone switching from a hair loss treatment spray with alcohol and propylene glycol to a serum with essential oils, questioning the absorption and effectiveness of the new product. The spray and serum both contain 0.3% finasteride and 6% minoxidil.

community Been on fin/min topical spray for 6 months and my hair is the worst it’s been

in Progress Pictures 6 upvotes 11 months ago

The user has been using a topical spray containing finasteride and minoxidil for six months but is experiencing increased hair shedding and concerns about its effectiveness. Suggestions include switching to oral finasteride and minoxidil, consulting a dermatologist, and checking for underlying health issues like thyroid function and nutrient deficiencies.

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learn Nanoxidil

learn Overview

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

Is finasteride safe? Studies report that most men tolerate finasteride 1 mg, but case series, regulatory labelling and patient reports describe sexual, mood and cognitive effects that some say persisted after stopping, and how often that happens is not established. It is a prescription-only medicine and is contraindicated in pregnancy.
Is Finasteride unbeatable or are there equally powerful alternatives? Trials report finasteride as the single medication with the strongest measured effect in male androgenetic alopecia, while dutasteride, minoxidil, topical finasteride, PRP, LLLT and microneedling all have supporting studies and are often reported to work better in combination. Finasteride, dutasteride and oral minoxidil are prescription-only, and several of these uses are off-label.
What does finasteride do to the female body? Find out its side effects. Finasteride is not approved for hair loss in women anywhere; the one controlled trial, in 137 postmenopausal women at 1 mg daily, found no benefit over placebo, while smaller uncontrolled studies at higher off-label doses report some improvement. It is contraindicated in pregnancy and crushed or broken tablets must not be handled.
All 5 questions on Finasteride →

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