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research Melanocortin receptors in fibroblastic cell types of the skin –in vitro and in vivo expression and functional relevance

1 citations , September 2004 in “Experimental Dermatology”

This study found that α-melanocyte-stimulating hormone may modulate inflammation in skin connective tissue by inhibiting proinflammatory effects in fibroblasts.

research Defining Skin Fibroblastic Cell Types Beyond CD90

31 citations , October 2018 in “Frontiers in Cell and Developmental Biology”

The conclusion is that CD90 is not a specific marker for fibroblast subtypes and better methods are needed to identify them.

research Immunohistochemical Pattern of CD34 Distribution in Different Types of Basal Cell Carcinoma and in Peritumoral Skin

January 2026 in “Medicina”

In this study, researchers documented the immunohistochemical distribution of CD34 in basal cell carcinoma and found distinct patterns of CD34 expression, with variations in CD34 positivity between different areas of BCC tumor stroma and adjacent skin regions.

Alterations of Collagen Type 1, Skin Fibroblasts, and Macrophages in the Scalp Following the Treatment of 1550-nm Erbium Glass Fractional Laser for Androgenetic Alopecia

research Alterations of collagen type 1, skin fibroblasts, and macrophages in the scalp following the treatment of 1550‐nm erbium glass fractional laser for androgenetic alopecia

June 2021 in “Journal of Cosmetic Dermatology”

Laser treatment shows promise for hair growth, but needs further research.

research Cell Type-specific Functions of the Lysosomal Protease Cathepsin L in the Heart

56 citations , October 2007 in “Journal of Biological Chemistry”

This study concluded that dilated cardiomyopathy in Ctsl-deficient mice is mainly due to the lack of cathepsin L in cardiomyocytes, with additional heart stress from the fur defect.

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Community Join

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community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

373 upvotes 6 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

community One year on finasteride has reversed some aging

in Chat 198 upvotes 11 months ago

Finasteride and minoxidil use resulted in a more youthful appearance and improved skin. There is debate about their effects on collagen and skin aging, with no solid evidence supporting significant changes due to finasteride.

community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

14 upvotes 3 years ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

community Comprehensive Microneedling Guide

292 upvotes 4 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community Summary of Procapil video by Haircafe

2 upvotes 1 year ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Epidermal Growth Factor

learn Beta Polypeptide

learn Vascular Endothelial Growth Factor

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