53 citations
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January 1986 in “Endocrinology” This rat study suggests that 5α-dihydrotestosterone plays a critical role in inhibiting nipple development in male fetuses by causing the regression of the nipple anlage in utero.
May 2025 in “Birth Defects Research” This study investigated the effects of YWS1903 in pregnant rats and found that high doses led to fetal growth reduction and skeletal malformations, while lower doses did not cause significant issues, establishing a no observed adverse effect level at 60 mg/kg.
March 2024 in “Birth defects research” This correspondence comments on a 2023 study by Nagaoka et al. regarding the maternal–fetal safety of an aqueous extract of Casearia sylvestris leaves in rats, but it does not provide new results or data.
July 2008 in “Planta Medica” This study found that Acanthus montanus leaves' aqueous extract is a developmental toxicant in rats, leading to several adverse effects on offspring when used during pregnancy.
4 citations
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March 2002 in “International journal of toxicology” In this study on tolerant rats, maternal and developmental toxicity from levo-alpha-acetyhnethadol hydrochloride were observed at all doses, without specific fetal toxicity or teratogenic effects.