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Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Finasteride temporarily lowers male rat fertility without affecting libido.

Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.

Vitamin D3 affects cell differentiation in specific skin areas.

Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

EVAL membranes help create cell structures that can regrow hair follicles.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Mouse genital development depends on male or female hormones for specific features.

Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

Understanding how fetal wounds heal could help improve healing in adults.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

Melatonin may help treat PCOS symptoms in rats.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.