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      learn Spironolactone

      Blood-pressure and diuretic drug with anti-androgen effects

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Minoxidil

      Vasodilator used on the scalp and, at low doses, as a tablet

      learn HMI-115

      Experimental antibody that blocks the prolactin receptor

      learn Dutasteride

      5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

      learn Bicalutamide

      • Can bicalutamide stop DHT from shrinking your hair follicles? Bicalutamide blocks androgens at the receptor rather than lowering DHT, and some dermatologists prescribe it off-label for women with pattern hair loss, although its US label says it should not be used in women. The one randomised trial (74 women, 2025) found it added no benefit to oral minoxidil, and the drug needs liver monitoring because its label warns of severe and fatal liver injury; it is contraindicated in pregnancy.

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