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      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Estradiol

      an estrogen promoting hair regrowth more commonly used in women

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn Cetirizine

      popular antihistamine showing promise for hair loss as an anti-inflammatory and prostaglandin inhibitor

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 10 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Rethinking DHT and Hair Loss: Are We Targeting the Wrong Enemy?

      in Research/Science 2 weeks ago
      Blocking DHT is not a cure for hair loss; instead, altering how scalp follicles respond to DHT might be more effective. Current treatments like topical finasteride and minoxidil are temporary solutions, and future approaches may involve gene therapy and bioengineering to change follicle behavior.

      community Don’t make the same mistake I did

      in Treatment  111 upvotes 3 years ago
      User noticed hair thinning at 26 and used minoxidil for 2 years with slight improvement. Stopping minoxidil led to dramatic hair loss, and others shared similar experiences, suggesting minoxidil and finasteride should be used consistently for best results.

      community 6 months of Mexican Finasteride (1.25mg every other day). It’s working slow but steady.

      in Progress Pictures  282 upvotes 1 year ago
      A user shared a 6-month hair loss treatment routine including Mexican finasteride (1.25mg every other day), daily minoxidil, bi-weekly dermarolling, and ketoconazole shampoo twice a week, noting significant crown growth and some frontal hairline improvement with initial side effects that have since subsided. They are seeking advice to improve results, particularly at the frontal hairline, without resorting to a hair transplant.