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GlossaryCalprotectin

protein in white blood cells indicating inflammation

Calprotectin is a protein found in white blood cells that plays a role in the body's immune response by binding to and sequestering metals needed by bacteria, thus inhibiting their growth. Elevated levels of calprotectin in stool or blood can be a marker of inflammation, often used to help diagnose conditions like inflammatory bowel disease (IBD) or infections.

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Tofacitinib for the Treatment of Three Immune-Mediated Conditions in One Patient: Ulcerative Colitis, Pyoderma Gangrenosum, and Alopecia Areata

research Tofacitinib for the Treatment of Three Immune-Mediated Conditions in One Patient: Ulcerative Colitis, Pyoderma Gangrenosum, and Alopecia Areata

5 citations , January 2021 in “Inflammatory Bowel Diseases”

Tofacitinib improved ulcerative colitis, skin ulcers, and hair loss in a patient who didn't respond well to other treatments.

research Treatment of Crohn's Disease and Concomitant Alopecia Areata With Tofacitinib

2 citations , November 2021 in “ACG Case Reports Journal”

Tofacitinib successfully treated hair loss in a Crohn's disease patient who previously used adalimumab.

research Infliximab-Associated Psoriasiform Alopecia

1 citations , October 2015 in “The American journal of gastroenterology”

Stopping infliximab and using strong topical steroids can regrow hair lost due to psoriasiform alopecia.

research Scattered Skin Eruptions in a Patient With Inflammatory Bowel Disease

1 citations , February 2021 in “Gastroenterology”

A woman with inflammatory bowel disease improved after treatment with ustekinumab for a rare skin condition associated with her disease.

research Inflammatory Bowel Disease: Pathogenesis, Diagnosis and Current Therapeutic Approach

13 citations , April 2022 in “Journal of Mind and Medical Sciences”

IBD treatment is complex and requires personalized approaches due to varying patient responses.

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community The link between hair loss and gut health

in Research/Science 59 upvotes 5 years ago

The conversation discusses the potential link between gut health and hair loss, with personal experiences of hair thinning and stomach issues shared. Some individuals found no success with common hair loss treatments like Minoxidil and Finasteride and are exploring the impact of gut health on hair growth.

community How uninformed the general public is about hair loss

in Chat 312 upvotes 2 years ago

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

community Reminder: Biotin supplementation is a scam.

in Product 115 upvotes 2 years ago

Biotin supplements are considered ineffective for hair loss and are not supported by evidence. People in the conversation have mixed experiences, with some noting benefits for nails and skin but not hair, while others continue to use biotin as part of their vitamin regimen.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 196 upvotes 9 months ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community I was a non-responder to Minoxidil before my esophagus surgery

in Research/Science 38 upvotes 2 years ago

The user experienced improved hair density after switching from 5mg to 2.5mg oral Minoxidil post-esophagus surgery, suggesting a possible link between gut health and hair growth. They theorize that long-term medication may have blocked nutrient intake, affecting hair regrowth.

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