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GlossaryCalprotectin

protein in white blood cells indicating inflammation

Calprotectin is a protein found in white blood cells that plays a role in the body's immune response by binding to and sequestering metals needed by bacteria, thus inhibiting their growth. Elevated levels of calprotectin in stool or blood can be a marker of inflammation, often used to help diagnose conditions like inflammatory bowel disease (IBD) or infections.

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research The Human Innate Immune Protein Calprotectin Elicits a Multi-Metal Starvation Response in Pseudomonas Aeruginosa

May 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

Calprotectin starves Pseudomonas aeruginosa of essential metals, affecting its growth and resistance.

Alopecia Areata: A Possible Extraintestinal Manifestation of Crohn's Disease

research Alopecia Areata: A Possible Extraintestinal Manifestation of Crohn's Disease

33 citations , June 2012 in “Journal of Crohn's and colitis”

Alopecia Areata might be linked to Crohn's disease.

Tofacitinib for the Treatment of Three Immune-Mediated Conditions in One Patient: Ulcerative Colitis, Pyoderma Gangrenosum, and Alopecia Areata

research Tofacitinib for the Treatment of Three Immune-Mediated Conditions in One Patient: Ulcerative Colitis, Pyoderma Gangrenosum, and Alopecia Areata

5 citations , January 2021 in “Inflammatory Bowel Diseases”

Tofacitinib improved ulcerative colitis, skin ulcers, and hair loss in a patient who didn't respond well to other treatments.

Scattered Skin Eruptions in a Patient With Inflammatory Bowel Disease

research Scattered Skin Eruptions in a Patient With Inflammatory Bowel Disease

1 citations , February 2021 in “Gastroenterology”

A woman with inflammatory bowel disease improved after treatment with ustekinumab for a rare skin condition associated with her disease.

Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient

research Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient

1 citations , January 2020 in “Journal of Crohn's and colitis”

Many people with inflammatory bowel disease have a vitamin C deficiency, which can lead to scurvy symptoms.

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