research Defective trophoblast function in mice with a targeted mutation of Ets2
Ets2 gene is crucial for placental development in mice.
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4 / 1000+ results research Author response: ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas
This study found that super-enhancers play a crucial role in driving malignant progression in squamous cell carcinoma stem cells through a regulatory network involving ETS2 transcription factors, highlighting the potential link between high ETS2 levels and poor patient outcomes in head and neck cancers.
research Decision letter: ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas
This study found that super-enhancers in squamous cell carcinoma stem cells are distinctly different from those in normal skin stem cells, with ETS2 playing a crucial role in promoting tumor growth.
research The Proximal Promoter of the Human Transglutaminase 3 Gene
In this study, sequences upstream of the TGM3 gene were found to regulate epithelial-specific gene expression in keratinocytes, suggesting potential applications in gene therapy.
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