This study found that a complex extract of Polygonatum sibiricum and Nelumbinis semen improved menopause symptoms in an ovariectomized rat model by enhancing blood lipid metabolism and reducing osteoporosis, without increasing risks of side effects like endometriosis, unlike conventional hormone-replacement therapy.
7 citations
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September 2023 in “Cancer Treatment Reviews” This review highlights the possible impact of side effects from endocrine therapy on quality of life, emphasizing that these can lead to poor adherence and early treatment discontinuation in patients with hormone receptor positive early breast cancer, potentially worsening survival outcomes.
2 citations
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December 1994 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study concluded that a regimen of transdermal estradiol and oral medroxyprogesterone acetate effectively reduces hirsutism while minimizing side effects in women with polycystic ovary syndrome.
January 2026 in “Clinics in Dermatology” This discussion examines the aesthetic symptoms of perimenopause, such as hot flashes and skin changes, and reviews management options like hormone replacement therapy and topical cosmetics, emphasizing the importance of consistency in treatment to maintain results.
November 2024 in “Frontiers in Medicine” In this review, the researchers highlighted the prevalent symptoms in cirrhosis patients, including pain, muscle cramps, sleep disturbances, and mental health issues, and emphasized the need for a comprehensive, multidisciplinary approach for symptom management to improve quality of life.