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    Glossary Epithelial Keratins

    Epithelial keratins are a group of fibrous proteins that form a key component of the cytoskeleton in epithelial cells, including those in the hair follicle. They play a crucial role in maintaining the structural integrity and resilience of hair and skin. In the context of hair loss, abnormalities or mutations in keratin genes can lead to conditions such as alopecia or other hair disorders, highlighting their importance in hair biology and health. Key distinguishing characteristics include their ability to form intermediate filaments, which provide mechanical support and protection to cells.

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    1. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles Differentiation · 1988 · 248 citations
    2. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues II. Concomitant and mutually exclusive synthesis of trichocytic and epithelial cytokeratins in diverse human and bovine tissues (hair follicle, nail bed and matrix, lingual papilla, thymic reticulum) Differentiation · 1988 · 187 citations
    3. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues Differentiation · 1988 · 124 citations
    4. Epithelial expression of cytokeratins 15 and 19 in vitiligo Journal of Cosmetic Dermatology · 2016 · 1 citations
    5. Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas. The Journal of Cell Biology · 1982 · 277 citations
    6. Immunolocalization of cytokeratins in some freshly fixed bovine epithelia. PubMed · 1991 · 4 citations
    7. Keratinisation status and cytokeratins of the human Meibomian gland epithelium Acta Ophthalmologica · 2009 · 5 citations
    8. The complement of native α-keratin polypeptides of hair-forming cells: A subset of eight polypeptides that differ from epithelial cytokeratins Differentiation · 1986 · 198 citations
    9. Cytokeratin 15 expression in central, centrifugal, cicatricial alopecia: new observations in normal and diseased hair follicles Journal of Cutaneous Pathology · 2011 · 14 citations
    10. Human epithelial stem cell survival within their niche requires “tonic” cannabinoid receptor 1‐signalling—Lessons from the hair follicle Experimental Dermatology · 2021 · 14 citations
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    1. Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling Reddit · 26 Oct 2025

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