November 2023 in “npj regenerative medicine” This study found that engineered reconstituted skin can form morphogenetic units that promote tissue patterning and hair regeneration, with certain signaling pathways restoring this ability in adult and fetal cells.
207 citations
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September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” The study found that reducing testosterone in male mice through castration or androgen antagonism significantly accelerated wound healing by decreasing inflammation, suggesting a potential therapeutic target for impaired healing in elderly men.
80 citations
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June 2008 in “Biomaterials” This study found that poly(ethylene-co-vinyl alcohol) membranes support the self-assembly of dermal papilla cells into compact spheroidal microtissues capable of inducing new hair follicles, suggesting potential for large-scale production for hair follicle regeneration.
January 2012 in “Elsevier eBooks” This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.
June 2026 in “Research Square” This study identified a group of dermal fibroblasts near hair follicle stem cells in mice that facilitate hair regeneration by creating a biomechanically compliant extracellular matrix, enhancing stem cell activation and promoting a positive feedback loop for tissue regeneration.