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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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4 / 4 resultslearn Epidermal Growth Factor
learn Low Level Laser Therapy
laser therapy for anti-inflammatory and likely insignificant hair regrowth effects
learn Thymosin Beta 4
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5 / 1000+ resultsresearch Delineation of Matriptase Protein Expression by Enzymatic Gene Trapping Suggests Diverging Roles in Barrier Function, Hair Formation, and Squamous Cell Carcinogenesis
Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.
research Increased Copy Number of the TERT and TERC Telomerase Subunit Genes in Cancer Cells
Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.
research Skin Cancer: Understanding the Transformation from Conventional to Advanced Treatment Approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Liposomes in Cosmeceuticals
Liposomes could improve how skin care products work but are costly and not very stable.
research Author Response: Loss of Dnmt3a and Dnmt3b Does Not Affect Epidermal Homeostasis but Promotes Squamous Transformation Through PPAR-γ
The study by Rinaldi et al. found that while Dnmt3a and Dnmt3b were not necessary for normal epidermal homeostasis in mice, their loss had significant effects on tumorigenesis. Specifically, the absence of Dnmt3a increased the initiation of squamous tumors, and the combined loss of both Dnmt3a and Dnmt3b led to more aggressive and metastatic squamous carcinomas. Dnmt3a promoted the expression of epidermal differentiation genes and inhibited lipid metabolism genes, including PPAR-γ. Inhibition of PPAR-γ reduced tumorigenesis in the absence of Dnmt3a, indicating that Dnmt3a and Dnmt3b played protective roles against tumorigenesis and that squamous carcinomas were sensitive to PPAR-γ inhibition.
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5 / 80 resultscommunity Clearing the air on how non-surgical treatments really work
Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.
community Is tazarotene potentially better than tretinoin in combination with topical minoxidil?
Tazarotene may be more effective than tretinoin when combined with topical minoxidil for hair loss due to its selective binding to RAR-beta and gamma, though it can cause irritation. Tazarotene's potency can lead to indirect inflammatory reactions despite potentially causing less irritation than tretinoin.
community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth
PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.
community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser
Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.
community (0.5 mg Dutasteride and 5 mg oral Minoxidil/day) 32 years old - Follow up on last post
The user experienced significant hair regrowth using 0.5 mg Dutasteride and 5 mg oral Minoxidil daily, after initially using finasteride and a lower dose of Minoxidil. They are considering dermarolling or derma stamping to improve results further before opting for a hair transplant.