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GlossaryEosinophilic Fasciitis

rare inflammatory condition causing thickened fascia and muscle pain

Eosinophilic Fasciitis, also known as Shulman's Syndrome, is a rare inflammatory condition where the fascia, the connective tissue surrounding muscles, becomes thickened and inflamed. This leads to swelling, pain, and stiffness in the arms and legs. The condition is characterized by an increased number of eosinophils, a type of white blood cell, in the affected tissue and sometimes in the blood. Diagnosis often involves a combination of clinical evaluation, blood tests, and a biopsy of the affected tissue.

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research Eosinophilic Fasciitis Associated With Tryptophan Ingestion

20 citations , February 1991 in “Archives of dermatology”

High doses of tryptophan may cause eosinophilic fasciitis.

research Evidence for Resident Memory T Cells and Necroptosis as Drivers of Fibrosis in Eosinophilic Fasciitis and Morphea

July 2025 in “Journal of Investigative Dermatology”

Resident memory T cells and necroptosis may drive fibrosis in eosinophilic fasciitis and morphea.

research Comparison of the Pathology of Fascia in Eosinophilic Myalgia Syndrome Patients and Idiopathic Eosinophilic Fasciitis

11 citations , January 1993 in “Dermatology”

EMS and EF both show similar skin and fascia changes, but EMS has more severe symptoms and nerve inflammation.

research Methotrexate Injection Site Reactions: Case Report and Literature Review

1 citations , March 2022 in “JAAD case reports”

Methotrexate injection site reactions are rare but can be managed by changing injection sites and using topical treatments.

research Connective Tissue Disorders

November 2014

Different connective tissue disorders have unique symptoms and treatments, with varying outcomes and often require ongoing care from a specialist.

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community I don't know what happened with me sudden hair loss from 6 months i use dut ,min , vitamin all things but no response

in Progress Pictures 18 upvotes 2 years ago

The person is experiencing sudden hair loss for six months and treatments like dutasteride, minoxidil, and vitamins are not working. Another person suggests the hair loss might not be androgenetic alopecia but could be telogen effluvium or an inflammatory condition.