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    Glossary Eosinophilic Fasciitis

    rare inflammatory condition causing thickened fascia and muscle pain

    Eosinophilic Fasciitis, also known as Shulman's Syndrome, is a rare inflammatory condition where the fascia, the connective tissue surrounding muscles, becomes thickened and inflamed. This leads to swelling, pain, and stiffness in the arms and legs. The condition is characterized by an increased number of eosinophils, a type of white blood cell, in the affected tissue and sometimes in the blood. Diagnosis often involves a combination of clinical evaluation, blood tests, and a biopsy of the affected tissue.

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    1. Eosinophilic Fasciitis Associated With Tryptophan Ingestion Archives of dermatology · 1991 · 20 citations
    2. 0960 Evidence for resident memory T cells and necroptosis as drivers of fibrosis in eosinophilic fasciitis and morphea Journal of Investigative Dermatology · 2025
    3. Comparison of the Pathology of Fascia in Eosinophilic Myalgia Syndrome Patients and Idiopathic Eosinophilic Fasciitis Dermatology · 1993 · 11 citations
    4. Scleroderma and L-tryptophan: A possible explanation of the eosinophilia-myalgia syndrome Journal of The American Academy of Dermatology · 1990 · 21 citations
    5. Methotrexate injection site reactions: Case report and literature review JAAD case reports · 2022 · 1 citations
    6. Connective Tissue Disorders 2014
    7. The eosinophilia-myalgia syndrome Clinics in Dermatology · 1994 · 4 citations
    8. Dermal Mucinosis in the Eosinophilia-Myalgia Syndrome Archives of Dermatology · 1990 · 8 citations
    9. The Dynamics of the Skin’s Immune System International Journal of Molecular Sciences · 2019 · 306 citations
    10. Highlights JAMA Dermatology · 2016
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