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GlossaryArtificial Skin (Engineered Skin Substitutes)

laboratory-created substitute mimicking natural human skin functions

Artificial skin, also known as synthetic skin or bioengineered skin, is a laboratory-created substitute designed to mimic the properties and functions of natural human skin. It is often used in medical treatments for burn victims, chronic wounds, and other skin injuries, providing a temporary or permanent covering that promotes healing and reduces the risk of infection. This engineered tissue can be composed of various materials, including collagen, silicone, and biodegradable polymers, and may incorporate living cells to enhance integration with the patient's own tissue.

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Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and After Transplantation

research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and After Transplantation

120 citations, August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

research Characterization of Hair Follicle Development in Engineered Skin Substitutes

41 citations, June 2013 in “PLOS ONE”

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

research Assessment of Replication Rates of Human Keratinocytes in Engineered Skin Substitutes Grafted to Athymic Mice

12 citations, June 2012 in “Wound Repair and Regeneration”

Regulating keratinocyte growth in engineered skin can improve wound healing.

Early-Stage Bilayer Tissue-Engineered Skin Substitute Formed by Adult Skin Progenitor Cells Produces an Improved Skin Structure In Vivo

research Early-Stage Bilayer Tissue-Engineered Skin Substitute Formed by Adult Skin Progenitor Cells Produces an Improved Skin Structure In Vivo

12 citations, September 2020 in “Stem cell research & therapy”

Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.

research Advanced Therapies for Skin Injuries

28 citations, September 2015 in “Wiener Klinische Wochenschrift”

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

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community Verteporfin update - donor hair regeneration human trial

in Research/Science 23 upvotes 2 years ago

A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.

community Topical T3 study - 1000% Growth. Anyone tried it?

in Research/Science 106 upvotes 3 years ago

The conversation discusses using T3 (triiodothyronine) as a topical treatment for hair growth, with some users noting it showed promising results in studies but lacked follow-up. Users express interest in trying T3 due to its potential effectiveness compared to Minoxidil.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Can Minoxidil be Aging My Skin?

in Minoxidil 6 upvotes 3 years ago

Minoxidil may cause skin aging effects like wrinkles and dark circles, but evidence is mixed. Alternatives like dermarolling and retinol are suggested.

community Evaluate your progress with an objective tool

in Progress Pictures 40 upvotes 6 months ago

The post discusses using ImageJ software to objectively track hair regrowth progress. The user is treating Androgen alopecia with dutasteride and minoxidil.

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