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GlossaryArtificial Skin (Engineered Skin Substitutes)

laboratory-created substitute mimicking natural human skin functions

Artificial skin, also known as synthetic skin or bioengineered skin, is a laboratory-created substitute designed to mimic the properties and functions of natural human skin. It is often used in medical treatments for burn victims, chronic wounds, and other skin injuries, providing a temporary or permanent covering that promotes healing and reduces the risk of infection. This engineered tissue can be composed of various materials, including collagen, silicone, and biodegradable polymers, and may incorporate living cells to enhance integration with the patient's own tissue.

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Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and After Transplantation

research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and After Transplantation

120 citations, August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

research Characterization of Hair Follicle Development in Engineered Skin Substitutes

41 citations, June 2013 in “PLOS ONE”

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Early-Stage Bilayer Tissue-Engineered Skin Substitute Formed by Adult Skin Progenitor Cells Produces an Improved Skin Structure In Vivo

research Early-Stage Bilayer Tissue-Engineered Skin Substitute Formed by Adult Skin Progenitor Cells Produces an Improved Skin Structure In Vivo

12 citations, September 2020 in “Stem cell research & therapy”

Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.

research Skin Graft Harvesting and Donor Site Selection

3 citations, August 2011 in “InTech eBooks”

The document concludes that skin grafts are essential for repairing tissue loss, with various types available and ongoing research into substitutes to improve outcomes and reduce donor site issues.

research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?

133 citations, July 2020 in “Cells”

Creating fully functional artificial skin for chronic wounds is still very challenging.

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community Topical T3 study - 1000% Growth. Anyone tried it?

WillMarshRun in Research/Science 106 upvotes 3 years ago

The conversation discusses using T3 (triiodothyronine) as a topical treatment for hair growth, with some users noting it showed promising results in studies but lacked follow-up. Users express interest in trying T3 due to its potential effectiveness compared to Minoxidil.

community Verteporfin update - donor hair regeneration human trial

Synizs in Research/Science 22 upvotes 2 years ago

A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

Busy-Order-9093 in Chat 237 upvotes 3 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 823 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Finasteride won’t make all your problems go away

idhke in Finasteride/Dutasteride 323 upvotes 1 year ago

A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

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