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Both methods improve hair density and thickness; double-spin may be more effective.

This study found that platelet-rich plasma prepared using a double-spin method may be more effective for treating female pattern hair loss than single-spin PRP, although VEGF concentration was unaffected by either preparation method.

This study found a strong positive correlation between vascular endothelial growth factor expression and microvessel density in the hair follicles of Liaoning cashmere goats during different fetal periods.

This study observed that stronger expression of ET-1 and SCF in early passages of cultured dermal papilla cells correlates with a higher ability to induce hair follicle regeneration.

This study observed that in spontaneously hypertensive rats, testosterone's effects on endothelium-dependent vasodilation involved reduced nitric oxide levels, increased oxidative stress, and greater reliance on endothelium-dependent hyperpolarization, with variations in these responses noted when testosterone was combined with either anastrozole or finasteride.