Study on VEGF in the Expression of Skin Hair Follicle and the Relationship with Microvessel Density by Liaoning Cashmere Goat in Fetal Period
January 2013
in “
China Animal Husbandry & Veterinary Medicine
”
TLDR VEGF increases in goat hair follicles during fetal development, boosting skin blood vessel density.
The study investigated the expression of vascular endothelial growth factor (VEGF) in the hair follicles of Liaoning cashmere goats during the fetal period using immunohistochemical methods. VEGF was found to be expressed in the hair papilla and inner root sheath of hair follicles after 75 days of fetal development. The study observed an increase in the average optical density of VEGF-positive areas and a growing trend in skin microvessel density (MVD). There was a strong positive correlation between the average optical density and MVD, with a correlation coefficient of 0.966 and a p-value of 0.007.