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GlossaryEctodysplasin A Receptor

protein crucial for hair, teeth, and gland development

The Ectodysplasin A Receptor (EDAR) is a protein that plays a crucial role in the development of hair, teeth, and certain glands. Mutations in the EDAR gene can lead to conditions like hypohidrotic ectodermal dysplasia, which is characterized by sparse hair, missing teeth, and reduced ability to sweat.

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research Epidermal Patterning and Induction of Different Hair Types During Mouse Embryonic Development

81 citations, September 2009 in “Birth defects research”

Different body areas in mice produce different hair types due to interactions between skin layers.

research Transcriptome Reveals Long Non-Coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin

37 citations, May 2018 in “Frontiers in physiology”

Certain RNA molecules are important for the development of wool follicles in sheep.

research KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin

82 citations, May 2009 in “Development”

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

research Convergent Decay of Skin-Specific Gene Modules in Pangolins

1 citations, December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

research Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats

1 citations, April 2023 in “Animals”

Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.