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Baseline Neutrophil-To-Lymphocyte Ratio Stratifies Early Trichoscopic Response To Platelet-Rich Plasma-Based Regimens In Non-Scarring Alopecia: A Real-World Cohort With Internal Validation Using An Interpretable Neural Network

research Baseline Neutrophil-to-Lymphocyte Ratio Stratifies Early Trichoscopic Response to Platelet-Rich Plasma–Based Regimens in Non-Scarring Alopecia: A Real-World Cohort with Internal Validation Using an Interpretable Neural Network

April 2026 in “Life”

In this study, baseline neutrophil-to-lymphocyte ratio (NLR) was associated with predicting early trichoscopic response in patients undergoing PRP-based treatment for non-scarring alopecia.

Cicatricial (Scarring) Alopecias: Comprehensive Review and Management

research Cicatricial (Scarring) Alopecias

44 citations , April 2012 in “American Journal of Clinical Dermatology”

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

research Early Diagnosis and Prompt Treatment Improves Quality of Life in Patients with Frontal Fibrosing Alopecia

2 citations , January 2019 in “Skin appendage disorders”

This article reports a case of frontal fibrosing alopecia in its early inflammatory stage that responded positively to intralesional steroid treatment.

research Scarring Alopecia in Pediatric Patients: A Narrative Review of Etiologies, Diagnosis, and Management Strategies

March 2026 in “Journal of Investigative Dermatology”

Early diagnosis and tailored treatment are crucial to prevent permanent hair loss and support self-esteem in children with scarring alopecia.

research Early Onset of Central Centrifugal Cicatricial Alopecia (CCCA) in Pediatric Patients: An Underrecognized Diagnosis

March 2026 in “Journal of Investigative Dermatology”

This study identified CCCA in 10 children of African descent, highlighting the occurrence of this scarring alopecia in patients under 18 and the importance of early diagnosis for better outcomes.

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community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Are Derma Rollers Actually Harmful in the Long Run?

in Microneedling 40 upvotes 1 year ago

Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

community Quote from Pelage (PP-405) Spokesperson...

122 upvotes 11 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community Burning/itching sensation & terrible tenderness on scalp accompanied with heavy shedding

1 upvotes 11 months ago

The user is experiencing increased hair shedding, scalp sensitivity, and itching despite using finasteride for four months, and has tried various shampoos without relief. They are advised to consult a dermatologist for potential scarring alopecia and consider other treatments like adding Dutasteride.

community 1mg of finasteride/2 sessions of Kenalog injections/ Clobetasol (4 months into treatment)

5 upvotes 2 months ago

The user is undergoing treatment for hair loss using finasteride, Kenalog injections, and Clobetasol, along with vitamin D and collagen supplements. They are considering additional treatments like minoxidil and microneedling, and there is discussion about whether the hair loss is due to stress, alopecia areata, or a scarring condition like lichen planopilaris.

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