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research A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice

106 citations, June 2005 in “Journal of Investigative Dermatology”

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

research Zinc as an Ambivalent but Potent Modulator of Murine Hair Growth In Vivo: Preliminary Observations

60 citations, October 2005 in “Experimental Dermatology”

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis

research Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis

53 citations, August 2019 in “American journal of human genetics”

FOXN1 gene variants cause low T cells and immune issues from birth.

research Corticosteroids for the Treatment of Duchenne Muscular Dystrophy

379 citations, May 2016 in “Cochrane library”

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease

research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease

26 citations, June 2018 in “The journal of immunology/The Journal of immunology”

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

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community These two strands of hair refuse to give in to DHT for some reason.

in Satire 994 upvotes 4 months ago

The conversation humorously discusses two resilient hair strands that resist DHT, with mentions of minoxidil and finasteride as ineffective treatments. Users joke about cloning the hairs and the mystery of baldness.

community Solving Hair Loss with Research at MIT

in Research/Science 594 upvotes 2 months ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community A Different Take on Curing MBP

16 upvotes 5 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community How does some people revive their scalps with minoxidil only?

in Minoxidil 26 upvotes 3 months ago

Some people respond better to minoxidil due to higher enzyme levels converting it to its active form. Minoxidil helps with hair regrowth but doesn't prevent hair loss; finasteride and other DHT inhibitors are needed for that.

community Is it possible to create an estrogen mesotherapy/topical that doesn't go systemic?

in Research/Science 6 upvotes 1 month ago

The conversation discusses the potential of using topical estrogen treatments for hair loss without systemic absorption, highlighting challenges and possible solutions like using estriol. It also mentions other treatments like topical finasteride, microneedling, and scalp massage, while noting the limitations and side effects of current options.

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