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Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo

68 citations, December 2011 in “Journal of Investigative Dermatology”

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

research Hair Germ Model In Vitro via Human Postnatal Keratinocyte-Dermal Papilla Interactions: Impact of Hyaluronic Acid

42 citations, January 2017 in “Stem cells international”

Adding hyaluronic acid helps create larger artificial hair follicles in the lab.

research Impact of Substrate Stiffness on Dermal Papilla Aggregates in Microgels

12 citations, January 2018 in “Biomaterials Science”

Softer hydrogel surfaces help maintain hair growth-related functions in skin cells.

research LncRNA-XIST Promotes Dermal Papilla Induced Hair Follicle Regeneration by Targeting miR-424 to Activate Hedgehog Signaling

11 citations, March 2020 in “Cellular Signalling”

XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.

Induction of Hair Follicle Dermal Papilla Cell Properties in Human Induced Pluripotent Stem Cell-Derived Multipotent LNGFR(+)THY-1(+) Mesenchymal Cells

research Induction of Hair Follicle Dermal Papilla Cell Properties in Human Induced Pluripotent Stem Cell-Derived Multipotent LNGFR(+)THY-1(+) Mesenchymal Cells

42 citations, February 2017 in “Scientific Reports”

Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.

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Community Join

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community HairClone developing cell replacement treatments for Hair Loss

6 upvotes 5 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community 4 months daily Min, Fin & Dermarolling once a week. I was very skeptical about Fin until other people started noticing my results.

in Progress Pictures 654 upvotes 3 years ago

A user's progress with using Minoxidil, Finasteride and Dermarolling to treat hair loss; some of the replies included reports of side effects, encouragement and advice on lighting.

community Help! Gyne after 20 years of taking Dut

in Finasteride/Dutasteride 39 upvotes 3 months ago

A 43-year-old experienced gynecomastia after 20 years of taking dutasteride and 7.5mg oral minoxidil. Suggestions include consulting an endocrinologist, checking hormones, and considering Nolvadex or DIM supplements.

community September 2021 update from Dr. Kang-Yell Choi [Korean "cure"]

in Research/Science 30 upvotes 3 years ago

Dr. Kang-Yell Choi's company, CK Regeon, is developing a drug called KY19382 for hair regeneration, which involves creating fine wounds to activate stem cells. The drug is in the formulation development stage, targeting markets like the US and Korea.

community 2020 updated guide for "I'm losing my hair, what do I do?". I've been taking Propecia for 12 years, and you can AMA.

in STARTER GUIDE 1681 upvotes 4 years ago

Hair loss treatments discussed include Propecia, Rogaine, Nizoral shampoo, and dermarolling. Users shared experiences and results, with some noticing improvements in hair growth and maintenance.

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