3 citations,
January 2021 in “Plastic and Aesthetic Research”
Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormanthairs rather than reverse thinning; patients often undervalue their hair loss severity.
1 citations,
January 2015 in “Journal of Aesthetic & Reconstructive Surgery”
Hair transplantation is the best treatment for hair loss, with new technologies improving results, and stem cell and gene therapies may treat severe baldness in the future.
Exosome injections stimulate hair growth by using exosomes' healing potential to awaken dormanthair follicles and promote new hair cell creation. The procedure increases scalp blood circulation, encourages collagen and elastin formation, and regenerates hair follicles, improving hair thickness and quality.
TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormanthair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.
Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
Hair loss treatments include finasteride and spironolactone. Low vitamin D levels may contribute to hair loss, and normalizing levels could potentially help regrowth.