3 citations,
January 2021 in “Plastic and Aesthetic Research”
Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormanthairs rather than reverse thinning; patients often undervalue their hair loss severity.
1 citations,
January 2015 in “Journal of Aesthetic & Reconstructive Surgery”
Hair transplantation is the best treatment for hair loss, with new technologies improving results, and stem cell and gene therapies may treat severe baldness in the future.
Finasteride and minoxidil can revive hairdormant for up to 7 years, with microneedling enhancing regrowth. Users report significant hair regrowth even after long periods of baldness.
PP405 is not a cure for hair loss but may reactivate dormanthair follicles, similar to minoxidil. It is unlikely to help with miniaturized or vellus hairs and is still in trial phases, with availability expected around 2030.
Exosome injections stimulate hair growth by using exosomes' healing potential to awaken dormanthair follicles and promote new hair cell creation. The procedure increases scalp blood circulation, encourages collagen and elastin formation, and regenerates hair follicles, improving hair thickness and quality.
Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.
TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormanthair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.