research Genetic Deletion of TNFα Inhibits Ultraviolet Radiation-Induced Development of Cutaneous Squamous Cell Carcinomas in PKCε Transgenic Mice via Inhibition of Cell Survival Signals
Deleting TNFα gene reduces skin cancer risk in certain mice.
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research DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice
Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
research Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis
Meis1 is crucial for skin health and tumor development.
research Conversion of C57Bl/6 Mice from a Tumor Promotion-Resistant to a Sensitive Phenotype by Enhanced Ornithine Decarboxylase Expression
Increased ornithine decarboxylase makes normally tumor-resistant mice more sensitive to tumors.
research Conversion of C57Bl/6 Mice from a Tumor Promotion-Resistant to a Sensitive Phenotype by Enhanced Ornithine Decarboxylase Expression
Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.
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