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research Does a male polycystic ovarian syndrome equivalent exist?

28 citations , July 2017 in “Journal of Endocrinological Investigation”

This study suggests that early onset androgenetic alopecia in men may indicate a male PCOS equivalent, possibly leading to higher risks of metabolic and cardiovascular disorders later in life.

research Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase

5 citations , February 1997 in “Bioorganic & Medicinal Chemistry”

This study found that among 17 beta-(N-ureylene-N,N'-disubstituted)-4-azasteroids, those with an N'-phenyl moiety were the most effective inhibitors of human type I 5 alpha-reductase.

research Evaluation of the effect of topical calcipotriol versus platelet-rich plasma versus a combination of both on patients with Alopecia Areata

November 2023 in “Research Square (Research Square)”

This double-blinded randomized clinical trial found that combining topical vitamin D analog (calcipotriol) and intra-lesion PRP led to a greater reduction in hair loss severity in alopecia areata patients compared to either treatment alone, with significant improvements observed across all groups.

research Differences in Demographic and Clinical Characteristics Among Subtypes of Female Pattern Hair Loss

August 2023 in “Clinical, Cosmetic and Investigational Dermatology”

In this study, the Hamilton-Norwood subtype of female pattern hair loss was associated with early onset and polycystic ovary syndrome, while the Ludwig pattern was more common overall.

research Group IID, IIE, IIF and III secreted phospholipase A2s

23 citations , August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids”

This article reviews the roles of lesser-known secreted phospholipase A2 isoforms in various biological processes, such as immune suppression, metabolic regulation, epidermal hyperplasia, and male reproduction, without reporting new clinical findings.

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community Pyrilutamide phase III clinical trial results released

in Research/Science 31 upvotes 2 years ago

Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

community Progress Pics 2 years fin 1mg, 1 year min

in Progress Pictures 277 upvotes 2 years ago

A user shared their hair loss progress after 2 years of finasteride and 1 year of minoxidil, along with occasional microneedling and regular exercise. They experienced initial shedding but saw significant improvement after 4 months.

community Fighting Seb Derm + MPB - Winning

72 upvotes 1 year ago

The user successfully managed hair regrowth by using a combination of finasteride, dutasteride, minoxidil, and specific shampoos to treat seborrheic dermatitis. They emphasize the importance of maintaining a healthy scalp and are considering food intolerance tests to further address inflammation.

community Important thing i discovered that makes ru58841 very effective

87 upvotes 7 months ago

RU58841 is more effective when mixed with isopropyl alcohol instead of minoxidil, as water in minoxidil degrades RU58841. Applying RU58841 separately from minoxidil, with an hour gap, enhances hair growth results.

community Topical Dutasteride Seems to Work

in Research/Science 22 upvotes 10 months ago

Topical dutasteride, particularly at 0.05%, shows greater hair density improvement than oral finasteride over 24 weeks, though hair thickness gains are similar. Some users report side effects with topical treatments, but others find them effective for maintaining hair without significant systemic absorption.

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SMP Specialist
Demii Foster
Doncaster, England, United Kingdom

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Demii Foster