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GlossaryDiscoid Lupus Erythematosus

chronic autoimmune condition causing red, scaly skin patches

Discoid Lupus Erythematosus (DLE) is a chronic autoimmune condition that primarily affects the skin, leading to the development of red, inflamed, and scaly patches, often on the face, scalp, and ears. These lesions can cause scarring and permanent hair loss if they occur on the scalp.

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research The Spectrum of Cutaneous Manifestations in Lupus Erythematosus: The Italian Experience

132 citations , July 2000 in “Lupus”

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

The Occurrence of Discoid Lupus Erythematosus Progressing to Systemic Lupus Erythematosus, with Overlapping ANCA-Associated Vasculitis, and Rheumatoid Arthritis Presenting as Papular-Purpuric Glove and Sock Syndrome

research The Occurrence of Discoid Lupus Erythematosus Progressing to Systemic Lupus Erythematosus, with Overlapping ANCA-Associated Vasculitis, and Rheumatoid Arthritis Presenting as Papular-Purpuric Glove and Sock Syndrome

May 2025 in “The Journal of Rheumatology”

A woman with skin and joint issues progressed from one type of lupus to another, highlighting the need to recognize complex conditions.

research Cutaneous Lesions in Systemic Lupus Erythematosus

32 citations , September 1989 in “Medical Clinics of North America”

Skin problems are common in lupus, important for diagnosis, and can be triggered by sunlight.

research Coexistence of Chronic Cutaneous Lupus Erythematosus and Frontal Fibrosing Alopecia

12 citations , March 2018 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

A patient had both chronic cutaneous lupus erythematosus and frontal fibrosing alopecia.

research A Study of Cutaneous Manifestations of Systemic Lupus Erythematosus in Malwa Region of India

April 2018 in “International Journal of Research in Dermatology”

Most patients with systemic lupus erythematosus in Malwa, India, show skin symptoms like photosensitivity and rashes.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Why do I have the feeling that this subreddit is flooded by Kintor employees?

in Chat 132 upvotes 1 year ago

Users discuss aggressive promotion of Koshine 826, suspecting Kintor employees are behind it. Concerns are raised about its effectiveness, with some preferring alternatives like finasteride and minoxidil.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 11 months ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community This is what Six years of DUT looks like

in Finasteride/Dutasteride 791 upvotes 3 years ago

User had success with dutasteride for hair loss after finasteride didn't work. Some experienced increased cholesterol and debated its relation to DHT.

community Anyone in the discord server for pp405 research?

in Chat 5 upvotes 5 months ago

The conversation is about users trying to regain access to a Discord server related to pp405 research, with differing opinions on the effectiveness of pp405 for hair loss. Specific treatments like Minoxidil, finasteride, and RU58841 are not mentioned in the conversation.

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