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research Gender-specific alteration of steroid metabolism and its impact on viral replication in a mouse model of hepatitis B virus infection

2 citations , September 2024 in “Animal Cells and Systems”

This study found that HBV infection altered steroid metabolism in male mice, significantly increasing levels of dehydroepiandrosterone and reducing dihydrotestosterone, which may suppress viral replication by affecting HBV promoter activity.

research Common Causes of Hair Loss

August 2022 in “JAMA”

Hair loss can be caused by hormones, illness, autoimmune disorders, or vitamin deficiencies, and treatments vary depending on the type.

research Androgens at the skin surface regulateS. aureuspathogenesis through the activation ofagrquorum sensing

2 citations , February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that host androgens like testosterone promote Staphylococcus aureus pathogenesis and skin infections by activating the agr quorum sensing system, revealing a mechanism for sex-dependent differences in these infections.

research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone

28 citations , November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

This study indicates that the normal human prostate is not a major contributor to circulating blood DHT concentrations in androgen-deficient patients receiving testosterone replacement therapy.

Hair Transplantation: Causes, Techniques, and Future Prospects

research Hair Transplantation

January 2010 in “Elsevier eBooks”

Hair transplantation is a treatment for hair loss mainly caused by genetics, with various techniques and potential complications, and results visible after 8-12 months.

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Community Join

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community How can my DHT be so low without Finasteride on cycle?

4 months ago

A user is curious why their DHT levels are not higher despite using 400mg of testosterone without finasteride, and wonders if zinc or GHK-Cu injections could be influencing this. Another user suggests that more testosterone typically leads to more DHT, but the user might be fortunate not to exceed normal DHT levels.

community GHK-Cu peptide injections - what is your experience?

13 upvotes 6 months ago

GHK-Cu peptide injections are discussed for hair growth, but users report mixed results and suggest focusing on DHT management first. Some users combine GHK-Cu with treatments like Minoxidil and Dutasteride, but emphasize its benefits for skin rather than hair.

community What else can make hair more sensitive to DHT?

17 upvotes 1 month ago

Genetics, inflammation, poor scalp circulation, stress, thyroid issues, low iron, vitamin D deficiency, steroids, age, fungal infections, stress, and creatine can increase hair sensitivity to DHT. Treatments mentioned include dutasteride, minoxidil, and Kre Alkalyn Monohydrate.

community My kid secretly took my avodart what should i do

in Is this regrowth? 42 upvotes 1 year ago

A child accidentally took Avodart, leading to concerns about DHT suppression and its effects. Users humorously discuss potential consequences and treatments like DHT injections and topical solutions.

community My transplant review - for anyone who wants to know how it works

8 upvotes 1 month ago

A user shared their experience with a hair transplant at Estenova in Istanbul, highlighting the painful injection process but overall satisfaction with the results. They also discussed the importance of using topical treatments and the potential for natural hair loss due to DHT, while other users shared their experiences with PRP and ongoing maintenance with finasteride and minoxidil.

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Learn

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learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Bicalutamide

Can bicalutamide stop DHT from shrinking your hair follicles? Bicalutamide blocks androgens at the receptor rather than lowering DHT, and some dermatologists prescribe it off-label for women with pattern hair loss. The published evidence is retrospective case series and one small pilot study, with no randomized trial; it is a prescription drug that requires liver monitoring and is contraindicated in pregnancy.

learn Exosomes

What does Fluridil do on the scalp, and how does it block the DHT hormone? Fluridil blocks DHT by binding to androgen receptors in hair follicles, preventing hair loss.

learn Metformin

Does metformin help control DHT levels that trigger androgenic alopecia? Metformin has been shown to lower circulating androgens in women with PCOS, but no published study has measured scalp DHT, 5-alpha reductase activity in the follicle, or hair density in anyone taking it — so its effect on pattern hair loss is untested, and it is not a DHT blocker.

learn Vitamin B5

Does Vitamin B5 prevent DHT-related androgenic alopecia? Vitamin B5 does not prevent DHT-related androgenic alopecia.

learn Baicapil

Losing hair from hormonal imbalance? Baicapil might block DHT without messing with your hormones. No published study shows that Baicapil blocks DHT — the only data on the ingredient itself is the manufacturer's own unpublished dossier, and the baicalin research behind the claim is cancer cell-line work in which the effect was explicitly independent of the androgen receptor.

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Clinics

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