Gender-Specific Alteration of Steroid Metabolism and Its Impact on Viral Replication in a Mouse Model of Hepatitis B Virus Infection

    September 2024 in “ Animal Cells and Systems
    Eun‐Sook Park, Juhee Won, Sung Hyun Ahn, Ah Ram Lee, D. H. Lee, Ju-Yeon Moon, Man Ho Choi, Kyun‐Hwan Kim
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    Studysummary This study found that HBV infection altered steroid metabolism in male mice, significantly increasing levels of dehydroepiandrosterone and reducing dihydrotestosterone, which may suppress viral replication by affecting HBV promoter activity.
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