research Synthesis and Biological Evaluation of Esters of 16-Formyl-17-Methoxy-Dehydroepiandrosterone Derivatives as Inhibitors of 5α-Reductase Type 2
Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
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research Novel Type 1 5a-Reductase Inhibitors With Antiproliferative Potential On LNCaP Cells
New compounds may help treat prostate cancer by reducing cell growth.
research New Ester Derivatives of Dehydroepiandrosterone as 5α-Reductase Inhibitors
New compounds may help treat prostate issues without affecting androgen receptors.
research Sex Hormones and Sarcopenia in Older Persons
Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
research A Missing Piece: The Spiny Mouse And The Puzzle Of Menstruating Species
The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
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5 / 98 resultscommunity Discussion: High DHT levels while on Fin+Dut with substantial progress (pics)
A user's experience with using 5AR inhibitors (Finasteride and Dutasteride) in combination with Minoxidil foam and microneedling, which resulted in substantial improvements to their crown density and hairline, despite high systemic levels of testosterone and dihydrotestosterone.
community Ray Peat: Testosterone Isn’t the Culprit, Prolactin and Cortisol Drive Hair Loss (2016)
Prolactin and cortisol are identified as key factors in hair loss, with stress hormones impacting hair shedding. Finasteride and minoxidil are effective treatments, while DHT's role and individual sensitivity are significant factors.
community How is dht not beneficial to you?
DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.
community Finasteride does deplete important nuero-active steroids
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.
community How do athletes maintain their hair transplants? Or do they not?
Athletes often use finasteride to maintain hair transplants, but some avoid it due to potential hormonal effects. Notable examples include Mo Salah and Conor McGregor, while LeBron James has had multiple procedures with varying success.